Results 51 to 60 of about 17,905 (274)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Toward global checks and balances
International organizations, International law, Informal international law, International tribunals, National courts, Judicial review, Checks and balances, Peer review, Global administrative law, K33,
Eyal Benvenisti, George Downs
core +1 more source
Penguatan Pengelolaan Keuangan Negara Melalui Mekanisme Checks and Balances System
Jurnal Konstitusi, 2018 Tulisan ini memfokuskan pada 2 (dua) isu utama, yaitu: pertama, bagaimana membangun mekanisme sistem checks and balances dalam mengelola keuangan negara, agar sejalan dengan upaya mewujudkan transparansi dan akuntabilitas pengelolaan keuangan negara ...
Hendar Ristriawan, Dewi Kania Sugiharti
doaj +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Why Do Voters Dismantle Checks and Balances? [PDF]
, 2013 Voters often dismantle constitutional checks and balances on the executive. If such checks and balances limit presidential abuses of power and rents, why do voters support their removal?
Acemoglu, Daron +7 more
core +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Checks and balances in weakly institutionalized countries
, 2014 Tesis (Magíster en Economía)--Pontificia Universidad Católica de Chile, 2014We extend a model by Acemoglu et al (2013) developed to explain this phenomenon, and include a measure of natural resource wealth in the government budget constraint.
Baragwanath Vogel, Kathryn +2 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Checks and balances, private information, and the credibility of monetary commitments [PDF]
The authors develop and test several new hypotheses about the anti-inflationary effect of central bank independence and exchange rate pegs in the context of different institutions and different degrees of citizen information about government policies ...
Keefer, Philip, Stasavage, David
core
Why Do Voters Dismantle Checks and Balances? [PDF]
Voters often dismantle constitutional checks and balances on the executive. If such checks and balances limit presidential abuses of power and rents, why do voters support their removal?
Ragnar Torvik +2 more
core +2 more sources