Results 61 to 70 of about 188,458 (274)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Penguatan Pengelolaan Keuangan Negara Melalui Mekanisme Checks and Balances System

open access: yesJurnal Konstitusi, 2018
Tulisan ini memfokuskan pada 2 (dua) isu utama, yaitu: pertama, bagaimana membangun mekanisme sistem checks and balances dalam mengelola keuangan negara, agar sejalan dengan upaya mewujudkan transparansi dan akuntabilitas pengelolaan keuangan negara ...
Hendar Ristriawan, Dewi Kania Sugiharti
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Managing Power Sharing of the State on Islamic Modern Society: a Case Study of Indonesia [PDF]

open access: yes, 2019
- On reasearch "checks and balances" in legal studies often raises high quality questions such as, does the checks and balances is a doctrine, principle, or legal theory, or maybe precisely the formula of power in politics. History been recorded, that in
Chandranegara, I. S. (Ibnu)   +1 more
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Rejuvinasi Sistem Checks And Balances dalam Sistem Ketatanegaraan di Indonesia [PDF]

open access: yes, 2013
Rejuvenation of Check and Balance System in Statehood System in Indonesia. Instead of delegated to only a person or an Institution, State Sovereignty shall be divided into some Institutions (separation of power).
Rahmatullah, I. (Indra)
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Constitucionalismo e Checks and Balances: Teoria e Pesquisa Empírica

open access: yesPrim@ Facie, 2012
Este artigo tem por objetivo apresentar e discutir as principais pesquisas empíricas sobre Constitucionalismo e Checks and Balances. O artigo está dividido da seguinte forma: a primeira parte versará sobre a trajetória do conceito de constitucionalismo ...
Saulo Felipe Costa   +2 more
doaj   +4 more sources

Pemilihan Presiden Dan Penciptaan Mekanisme 'Checks and Balances': Menuju Penciptaan Sistem Presidensial Murni

open access: yesJSP: Jurnal Ilmu Sosial dan Ilmu Politik, 2002
The attempt to question the legitimacy of President Abdurrahman Wahid has led to reemergence of the idea of having a direct election for the filling the President post, instead of having an indirect election, namely through the People's Consultative ...
Afan Gaffar
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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