Results 111 to 120 of about 4,480,665 (367)
The importance of iron chelation and iron availability during PpIX-induced photodynamic therapy [PDF]
, 2015 This is the accepted version of the article. Please cite the published version which is available via the DOI link in this record.Background: Protoporphyrin IX (PpIX)-induced photodynamic therapy (PDT) is being utilised as a topical method of localised ...
Curnow, Alison, Pye, Andrew
core +1 more source
Journal of Basic and Clinical Pharmacy, 2016 Objectives: There is a need to remove excess iron with iron chelation therapy (ICT) to avoid the serious clinical sequelae associated with iron overload in patients with beta thalassemia major (BTM) and sickle cell anemia (SCA). Due to the effects of the
S. P. Senol +5 more
semanticscholar +1 more source
Ionic Conductive Textiles for Wearable Technology
Advanced Materials, EarlyView.Recent advances in ionic conductive textiles for wearable technology are summarized, with a focus on soft ionic conductors that exhibit skin‐like flexibility and tissue‐like ion dynamics. Their structures, key characteristics, manufacturing methods, and diverse applications are reviewed.
Lingtao Fang, Yunlu Zhou, Qiyao Huang
wiley +1 more source
Comorbidities in aging patients with sickle cell disease. [PDF]
, 2018 Sickle cell disease (SCD) in general and sickle cell anemia in particular is a highly complex disorder both at the molecular and clinical levels. Although the molecular lesion is a single-point mutation, the sickle gene is pleiotropic in nature causing ...
Ballas, Samir K.
core +2 more sources
Advanced Materials, EarlyView.AIE‐active tetranuclear Ir(III) complex Ir‐4 as a sonosensitizer/sonocatalyst is formulated into a nanoplatform with an H2S donor. Ir‐4@S‐R NPs achieves combined endogenous NIR chemiluminescence imaging, sonodynamic therapy and release of H2S in situ by a bioorthogonal sonocatalytic reaction in vivo, achieving safe thrombolysis and anti‐inflammatory ...
Zihan Wu +11 more
wiley +1 more source
A schistosome [beta] subunit remodels inactivation of a calcium channel _via_ an N-terminal polyacidic motif [PDF]
, 2010 The beta subunit of high voltage-activated Ca (Cav) channels targets the pore forming [alpha]~1~ subunit to the plasma membrane and defines the biophysical phenotype of the Cav channel complex. Cav channel inactivation following activation and opening is
Robert M. Greenberg +1 more
core +1 more source
Liver disease in chelated transfusion-dependent thalassemics: the role of iron overload and chronic hepatitis C. [PDF]
, 2008 Iron overload and hepatitis virus C infection cause liver fibrosis in thalassemics. In a monocentric retrospective analysis of liver disease in a cohort of 191 transfusion-dependent thalassemics, in 126 patients who had undergone liver biopsy (mean age ...
ALMASIO, Pier Luigi +12 more
core +1 more source
Advanced Materials, EarlyView.A multifunctional nanomedicine co‐loading of the α‐emitter 223RaCl2 within iron‐based MOFs is developed. Precisely targeted to mitochondria, it exploits the full decay spectrum to synchronize three therapeutic actions: direct α‐particle ionization, self‐powered catalytic H2O2 generation via secondary electrons, and immunogenic cell death induction ...
Xian Li +7 more
wiley +1 more source
Sex and Gender Differences in Iron Chelation
BiomedicinesBackground/Objectives: In the absence of physiological mechanisms to excrete excessive iron, the administration of iron chelation therapy is necessary.
Sarah Allegra +3 more
doaj +1 more source
A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS [PDF]
, 2011 International audienceTo better understand the detection and management of iron overload in transfusion-dependent patients with myelodysplastic syndromes (MDS), a 15-min web- or paper-based survey was conducted among 338 European physicians from 27 ...
Fenaux, Pierre, +3 more
core +4 more sources