Results 261 to 270 of about 4,480,665 (367)

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

open access: yesCancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu   +16 more
wiley   +1 more source

Staphylococcus aureus AgrA Modulators From South African Antimicrobial Plants

open access: yesChemistry &Biodiversity, EarlyView.
The study workflow utilized validated in silico [molecular docking, fingerprinting, pharmacokinetics prediction, molecular dynamics (MD) simulation, ligand‐protein contact maps] tools to bioprospect a wide variety of metabolites surveyed from South African plants with antimicrobial activities, and target them against the key S.
Christiana Eleojo Aruwa, Saheed Sabiu
wiley   +1 more source

ADVANCES IN THALASSEMIA MANAGEMENT AND CHELATION THERAPY

open access: yesHematology, Transfusion and Cell Therapy
Autosomal recessive thalassemias are a heterogeneous group of diseases characterized by hypochromic microcytic anemia, which develops as a result of defective synthesis of one or more of the hemoglobin (Hb) chains.
Barbaros Şahin Karagün
doaj  

Use of rapid cardiac magnetic resonance imaging to guide chelation therapy in patients with transfusion-dependent thalassaemia in India: UMIMI study. [PDF]

open access: yesEur Heart J Qual Care Clin Outcomes, 2022
Medina KM   +22 more
europepmc   +1 more source

Management of iron overload in myelodysplastic syndromes: combined deferasirox and deferoxamine in a patient with liver disease [PDF]

open access: yes, 2016
AVILIA, SIMONA   +7 more
core   +1 more source

Synthesis, Characterization, Biological Evaluation, DFT Calculations, and Molecular Docking Study of Transition Metal Complexes Derived From a Schiff Base Ligand

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The escalating global challenge of antibiotic resistance amid rising oxidative stress emphasizes the critical necessity for innovative antimicrobial strategies. This study, reported synthesis of Schiff base ligand, (Z)‐2‐[(4‐nitrobenzylidene)amino]phenol (HL), derived from condensation between 2‐aminophenol and 4‐nitrobenzaldehyde, and it Co ...
Ibrahim Waziri   +7 more
wiley   +1 more source

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