Results 111 to 120 of about 335,323 (145)

Plant Alkaloids as Promising Anticancer Compounds with Blood-Brain Barrier Penetration in the Treatment of Glioblastoma: In Vitro and In Vivo Models. [PDF]

Molecules
Ożarowski M, Karpiński TM, Czerny B, Kamiński A, Seremak-Mrozikiewicz A.   +4 more
europepmc   +1 more source

Classification and Anti-<i>Streptococcus mutans</i> Mechanism Summary of Chinese Botanical Products. [PDF]

Pathogens
Li Y, Fang Z, Huang R.
europepmc   +1 more source

Comprehensive Analysis Reveals That ISCA1 Is Correlated with Ferroptosis-Related Genes Across Cancers and Is a Biomarker in Thyroid Carcinoma. [PDF]

Genes (Basel)
Xiong D, Li Z, Zuo L, Ge J, Gu Y, Zhang E, Zhou X, Yu G, Sang M.   +8 more
europepmc   +1 more source

Potential of isoquinoline-alkaloid-rich <i>Papaveraceae</i> extracts against bacteria causing ocular infections - <i>In vitro</i> and <i>In vivo</i> study. [PDF]

Front Pharmacol
Dzięgielewska M, Zielińska S, Khan T, Qudus MS, Dudek B, Brożyna M, Kozłowska W, Matkowski A, Bartoszewicz M, Sun Y, Junka A.   +10 more
europepmc   +1 more source

N-(2-Hydroxyphenyl)-2-Propylpentanamide (HO-AAVPA) Induces Apoptosis and Cell Cycle Arrest in Breast Cancer Cells, Decreasing GPER Expression. [PDF]

Molecules
Prestegui Martel B, Chávez-Blanco AD, Domínguez-Gómez G, Dueñas González A, Gaona-Aguas P, Flores-Mejía R, Somilleda-Ventura SA, Rodríguez-Cortes O, Morales-Bárcena R, Martínez Muñoz A, Mejia Barradas CM, Mendieta Wejebe JE, Correa Basurto J.   +12 more
europepmc   +1 more source

Chelerythrine inhibits esophageal squamous cell carcinoma progression via PINK1-Parkin-mediated mitophagy. [PDF]

J Transl Med
Zhou Y, Wang Z, Zhao H, Liu Y, Lin Y, Zhang J, Li X, Zhang B, Xie J, An X, Zhang L, Shi S, Zhang K, Liu K.   +13 more
europepmc   +1 more source

Deep eutectic solvents for green extraction and separation of bioactive compounds from traditional Chinese medicines. [PDF]

Chin Med
Ali A, Li R, Zhu R, Mahmood S, Chen Q, Yao S.   +5 more
europepmc   +1 more source

Nanotechnology Meets Phytotherapy: A Cutting-Edge Approach to Treat Bacterial Infections. [PDF]

Int J Mol Sci
Pacyga K, Pacyga P, Szuba E, Viscardi S, Topola E, Duda-Madej A.   +5 more
europepmc   +1 more source

The role of leptin in regulation of the soluble amyloid precursor protein α (sAPPα) levels in lung cancer cell media. [PDF]

Sci Rep
Haddad B, Khalil J, Al Khashali H, Ray R, Goel S, Darweesh B, Coleman KL, Wozniak C, Ranzenberger R, Lopo B, Guthrie J, Heyl D, Evans HG.   +12 more
europepmc   +1 more source

Chelerythrine Chloride is an Affinity-Labeling Inactivator of CYP3A4 by Modification of Cysteine239

Journal of Medicinal Chemistry
Chelerythrine chloride (CHE) is a quaternary benzo[c]phenanthridine alkaloid with an iminium group that was found to cause time- and concentration-dependent inhibition of CYP3A4. The loss of CYP3A4 activity was independent of NADPH. CYP3A4 competitive inhibitor ketoconazole and nucleophile N-acetylcysteine (NAC) slowed the inactivation.
Xu Mao, Guode Zhao, Qian Wang, Junqi He, Ying Liu, Ting Liu, Weiwei Li, Ying Peng, Jiang Zheng   +8 more
core   +4 more sources