Results 121 to 130 of about 335,323 (145)
Some of the next articles are maybe not open access.
Antiplatelet effects of chelerythrine chloride isolated from Zanthoxylum simulans
Biochimica Et Biophysica Acta - Molecular Cell Research, 1990Chelerythrine chloride is an antiplatelet agent isolated from Zanthoxylum simulans. Aggregation and ATP release of washed rabbit platelets caused by ADP, arachidonic acid, PAF, collagen, ionophore A23187 and thrombin were inhibited by chelerythrine chloride. Less inhibition was observed in platelet-rich plasma.
Ih-Sheng Chen +2 more
exaly +3 more sources
Chelerythrine chloride inhibits Zika virus infection by targeting the viral NS4B protein
Antiviral Research, 2023Zika virus (ZIKV) is a mosquito-borne virus that has re-emerged as a significant threat to global health in the recent decade. Whilst infections are primarily asymptomatic, the virus has been associated with the manifestation of severe neurological complications. At present, there is still a lack of approved antivirals for ZIKV infections.
Justin Jang Hann Chu +2 more
exaly +3 more sources
Chelerythrine Chloride And Its Effects On Phonotactic Behavior In Female Crickets Acheta Domesticus [PDF]
, 2023 Selective phonotaxis by female crickets has been shown to be variable. Mechanisms which underlie such behavioral variability are being studied. Juvenile Hormone III is a neuromodulator that has been shown to increase selectivity in phonotactic behavior of female crickets.
Shin, Heaven, Shin, Haneul
openaire +2 more sources
Chelerythrine chloride binding of guanosine in aqueous solution
Chinese Chemical Letters, 2009Abstract In this work, the interaction between chelerythrine (CHE) and guanosine is studied using UV–vis and fluorescence measurements at various temperatures. The UV–vis spectra show that the increasing guanosine concentrations result in the decreasing absorption intensity and red shift of CHE E absorption band (267 nm). The fluorescence spectra are
Fan Liu +5 more
exaly +2 more sources
A Spectral Study of the Interaction Between Chelerythrine Chloride and Adenosine
Spectroscopy Letters, 2007Abstract The possible anticancer mechanisms of chelerythrine (CHE) and its interactions with adenosine were investigated by UV‐visible spectrophotometric and spectrofluorimetric measurements and by thermodynamic calculations. The binding of CHE to adenosine could be characterized by the hypochromic and bathochromic effects in the absorption bands and ...
Xionghui Wei, Quanling Suo
exaly +2 more sources
A spectral study of the interaction between chelerythrine chloride and cytidine
Chinese Chemical Letters, 2007Abstract To study the possible anticancer mechanisms of chelerythrine (CHE), and its interactions with cytidine were investigated by UV–vis spectrophotometric and spectrofluorimetric measurements and by thermodynamic calculations. The binding of CHE to cytidine could be characterized by the hypochromic and bathochromic effects in the absorption bands,
Xiao Yan Zhang +2 more
exaly +2 more sources
Archives of Pharmacal Research, 2011
The objective of this study was to evaluate the antitumor activity of chelerythrine chloride (CHE) and investigate its potential apoptotic induction mechanism in SMMC-7721 cells. Our results suggested that the proliferation of SMMC-7721 cells was inhibited by CHE in a time and dose dependent manner, with a significant accumulation in S phase, and the ...
Zhengfu Zhang
exaly +3 more sources
The objective of this study was to evaluate the antitumor activity of chelerythrine chloride (CHE) and investigate its potential apoptotic induction mechanism in SMMC-7721 cells. Our results suggested that the proliferation of SMMC-7721 cells was inhibited by CHE in a time and dose dependent manner, with a significant accumulation in S phase, and the ...
Zhengfu Zhang
exaly +3 more sources
Phytotherapy Research, 2023
AbstractChelerythrine chloride (CHE) is a benzodiazepine alkaloid derived from natural herbs with significant anti‐tumor and anti‐inflammatory activities. However, the exact role and underlying mechanisms of CHE in colorectal cancer (CRC) remain unclear. Therefore, this study is aimed to investigate the influence of CHE on the progression of CRC.
Dan Liang +7 more
openaire +2 more sources
AbstractChelerythrine chloride (CHE) is a benzodiazepine alkaloid derived from natural herbs with significant anti‐tumor and anti‐inflammatory activities. However, the exact role and underlying mechanisms of CHE in colorectal cancer (CRC) remain unclear. Therefore, this study is aimed to investigate the influence of CHE on the progression of CRC.
Dan Liang +7 more
openaire +2 more sources
ChemInform Abstract: TOTAL SYNTHESIS OF CHELERYTHRINE CHLORIDE THROUGH A NOVEL ROUTE
Chemischer Informationsdienst, 1974AbstractUmsetzung des aus dem Oxim (I) durch Semmler‐Wolff‐Aromatisierung erhältlichen Naphthylamins (II) mit dem Bromaldehyd (III) liefert das Anil (IV), das zur Base (V) reduziert wird.
S. V. KESSAR, M. SINGH, P. BALAKRISHNAN
openaire +1 more source
Shock, 2000
Polymorphonuclear leukocytes (PMN) play a primary role in the initiation and propagation of inflammatory responses. PMN apoptosis is a major mechanism associated with the resolution of inflammatory reactions. Understanding mechanisms associated with PMN apoptosis will be of critical value in the development of novel pharmacological treatment strategies
J F, Sweeney +3 more
openaire +2 more sources
Polymorphonuclear leukocytes (PMN) play a primary role in the initiation and propagation of inflammatory responses. PMN apoptosis is a major mechanism associated with the resolution of inflammatory reactions. Understanding mechanisms associated with PMN apoptosis will be of critical value in the development of novel pharmacological treatment strategies
J F, Sweeney +3 more
openaire +2 more sources