Results 251 to 260 of about 198,073 (289)

Epithelial TRIM27 Inhibits Intestinal Inflammation in Ulcerative Colitis by the USP7/TRIM27‐IKK Double Negative‐Feedback

Advanced Science, EarlyView.
ABSTRACT The E3 ubiquitin ligase tripartite motif 27 (TRIM27) is a negative regulator of NF‐κB activation and the innate immune response, and TRIM27 deficiency significantly impairs dextran sulfate sodium (DSS)‐induced colitis. The function of TRIM27 in intestinal epithelial cells (IECs), the mechanism by which TRIM27 inhibits the NF‐κB pathway and its
Weimin Xu, Zhebin Hua, Zhujiang Dai, Shasha Zhang, Yihan Jiang, Wensong Ge, YingWei Chen, Zhongchuan Wang, Bing Zhang, Chen‐Ying Liu, Peng Du   +10 more
wiley   +1 more source

Exploring the toxic mechanism of excessive intake of naringin on drug-induced liver injury using network toxicology and experiment validation strategy. [PDF]

BMC Pharmacol Toxicol
Ding Y, Yu T, He J, Peng C, Wang X, Huang J.   +5 more
europepmc   +1 more source

Synergistic Sunlight‐Activated Photodynamic and Near‐Infrared‐Induced Mild Photothermal Therapy for Infected Wound Healing Using Functionalized Nano‐Bi2WO6 Composites

Advanced Science, EarlyView.
This work proposes a multifunctional Bi2WO6:Yb,Er@CuS@CS nanocomposite that integrates photodynamic therapy (PDT), near‐infrared‐triggered photothermal therapy (PTT), and Cu2+ release for infected wound repair. The nanocomposite demonstrates enhanced antibacterial efficacy via combined PDT, PTT, and Cu2+ release, effective immunomodulatory by mild ...
Yihao Sun, Liangrui He, Zhijun Shen, Yuxin Zhang, Yizhang Tang, Xujiang Yu, Jisi Zheng, Moran Huang, Wanwan Li, Lei Wang   +9 more
wiley   +1 more source

Naproxen as a cause of acute cholestatic hepatitis: a case report. [PDF]

J Med Case Rep
El Maimouni C, Jiménez-Esquivel N, Duarte A, Díaz A, Salgado MC, Forns X, Reverter E.   +6 more
europepmc   +1 more source

Drug-Induced Liver Injury Associated With the Angiotensin II Receptor Blocker Losartan in a 59-Year-Old Woman With Hypertension: A Case Report. [PDF]

Am J Case Rep
Al-Ajaj A, Melki W.
europepmc   +1 more source

Decoding liver injury in cystic fibrosis: How to tell drug-induced liver injury from cystic fibrosis liver disease. [PDF]

World J Gastroenterol
Lee J, Yekula A, Wexler A, Zhuang W, Elangovan A, Rosario J, Burger P, Ramaraju G, Addissie B, Lim N, Narkewicz MR, Twohig P.   +11 more
europepmc   +1 more source

Dose- and Organ-Specific Dual Effects of MitoTempo in Paracetamol-Induced Hepatorenal Toxicity in Mice. [PDF]

Biomolecules
Orhan H, Atmaca K, Aladağ B, Kotmakçı M.   +3 more
europepmc   +1 more source

Self-assembled PEGylated nanoparticles based on Elafibranor derivative 3d for the treatment of metabolic dysfunction-associated steatohepatitis. [PDF]

J Biol Eng
Yu J, Wang J, Li S, Bai S, Wang X, Ban Y, Zhang S, Yu Y, Liu J, Liu Z, Galons H, Zhang Y, Yu P, Xiang C, Teng Y.   +14 more
europepmc   +1 more source