Results 111 to 120 of about 4,372,191 (364)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

The Molecular Clouds in a Section of the Third Galactic Quadrant: Observational Properties and Chemical Abundance Ratio between CO and its Isotopologues

The Astronomical Journal, 2023
We compare the observational properties between ^12 CO, ^13 CO, and C ^18 O and summarize the observational parameters based on a 7069-cloud sample from the Milky Way Imaging Scroll Painting CO survey in a section of the third Galactic quadrant.
Chen Wang, Haoran Feng, Ji Yang, Xuepeng Chen, Yang Su, Qing-Zeng Yan, Fujun Du, Yuehui Ma, Jiajun Cai   +8 more
doaj   +1 more source

CHEMICAL ABUNDANCES IN A SAMPLE OF RED GIANTS IN THE OPEN CLUSTER NGC 2420 FROM APOGEE [PDF]

, 2016
NGC 2420 is a ∼2 Gyr old well-populated open cluster that lies about 2 kpc beyond the solar circle, in the general direction of the Galactic anti-center.
D. Souto, K. Cunha, V. Smith, C. Prieto, M. Pinsonneault, O. Zamora, D. A. Garc'ia-Hern'andez, S. Mészáros, J. Bovy, A. Pérez, F. Anders, D. Bizyaev, R. Carrera, P. Frinchaboy, J. Holtzman, I. Ivans, S. Majewski, M. Shetrone, J. Sobeck, K. Pan, B. Tang, S. Villanova, D. Geisler   +22 more
semanticscholar   +1 more source

Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation

FEBS Letters, EarlyView.
The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen, Zenon Toprakcioglu, Michele Vendruscolo   +2 more
wiley   +1 more source

About the chemical composition of delta Scuti - the prototype of the class of pulsating variables

, 2004
We present chemical abundances in the photosphere of $\delta$ Scuti -- the prototype of the class of pulsating variables -- determined from the analysis of a spectrum obtained at Terskol observatory 2 meter telescope with resolution $R=52,000$, signal to
Gopka, V., Kang, F., Kim, C., Musaev, F., Yushchenko, A.   +4 more
core   +1 more source

CHAOS I. DIRECT CHEMICAL ABUNDANCES FOR H II ?> REGIONS IN NGC 628 [PDF]

, 2015
The CHemical Abundances of Spirals (CHAOS) project leverages the combined power of the Large Binocular Telescope (LBT) with the broad spectral range and sensitivity of the Multi Object Double Spectrograph (MODS) to measure “direct” abundances (based on ...
D. Berg, E. Skillman, K. Croxall, R. Pogge, J. Moustakas, Mara Johnson-Groh   +5 more
semanticscholar   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

The abundance of HCN in circumstellar envelopes of AGB stars of different chemical types

, 2013
A multi-transition survey of HCN (sub-) millimeter line emission from a large sample of AGB stars of different chemical type is presented. The data are analysed and circumstellar HCN abundances are estimated.
Bieging, J. H., Lindqvist, M., Marvel, K. B., Olofsson, H., Ramstedt, S., Schöier, F. L.   +5 more
core   +1 more source

Chemical abundances in a UV-selected sample of galaxies [PDF]

Monthly Notices of the Royal Astronomical Society, 2002
17 pages, 10 figures, and 2 tables.
Contini, Thierry, Treyer, Marie A., Sullivan, Mark, Ellis, Richard S.   +3 more
openaire   +6 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source