Results 51 to 60 of about 5,861,914 (301)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Antibacterial and Antifungal Effects of Chemical Additives Used in Poultry Production: An In Vitro Minimum Inhibitory Concentration Study

Poultry
The application of chemical additives in poultry litter management aims to control the microbial population and reduce harmful gases. We conducted in vitro analyses to determine and compare the minimum inhibitory concentration (MIC) of commercial ...
Joyce de Jesus Mangini Furlan, Melina Lima Santos, Silvia Helena Seraphin de Godoy, Ricardo Luiz Moro de Sousa   +3 more
doaj   +1 more source

Electrochemical Mechanism of the Preparation of High-Purity Indium by Electrodeposition

Frontiers in Chemistry, 2022
Indium is a crucial material and is widely used in high-tech industries, and electrodeposition is an efficient method to recover rare metal resources. In this work, the electrochemical behavior of In3+ was investigated by using different electrochemical ...
Zhongmin Hou, Zhongmin Hou, Xiaomin Wang, Jidong Li, Zhen Li, Yiyong Wang, Hongxuan Xing   +6 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Influence of the Spectral Composition of Illuminating Light Sources on Biometric and Phytochemical Characteristics of Ocimum basilicum L.

Photonics, 2023
Precise adaptation of the greenhouse lighting spectrum to basic photophysiological processes can effectively and directionally stimulate plant growth and development.
Mariya Degtereva, Yevgeniy Levin, Anastasia Gubina, Aleksandr Degterev, Ivan Lamkin, Georgii Konoplev, Sergey Tarasov, Andrei Whaley, Anastasiia Whaley, Ivan Suloev, Alexandra Danilova, Konstantin Gusev, Denis Maimistov   +12 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Intrinsic edge dislocations promote high-temperature strength and ductility in additively manufactured refractory high-entropy alloys

Nature Communications
Refractory high-entropy alloys (RHEAs) hold promise for applications in extreme environments. However, conventional as-cast RHEAs are constrained by the trade-off between strength and ductility, necessitating time- and energy-intensive post-processing ...
Chunhuan Guo, Bo Jiao, Fengchun Jiang, Wei Chen, Wenyuan Wang, Cheng Zhang, Bozhao Zhang, Huabing Gao, Tao Dong, Wenyao Sun, Zubin Chen, Haixin Li, Zhenlin Yang, Shiteng Zhao, Jun Ding, Robert O. Ritchie   +15 more
doaj   +1 more source

An Evaluation of the Effectiveness of a Chemical Additive on the Fermentation Quality, Aerobic Stability and Microbial Communities of High-Moisture Corn at 35 °C and 5 °C

Fermentation
This study evaluated a compound chemical additive (CA) composed of potassium sorbate, sodium benzoate, and sodium nitrite. Potassium sorbate is suitable for high-temperature ensiling, while sodium nitrite functions well under low-temperature conditions ...
Ziyan Wang, Yumeng Yan, Lingzhi Kong, Yu Zhang, Zhixian Zhao, Kainan Xu, Muyang Li, Lei Zhao, Fangfang Zhao, Yanbing Li   +9 more
doaj   +1 more source