This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao+6 more
wiley +1 more source
FAERS based disproportionality analysis and network pharmacology investigation of taxanes associated drug induced liver injury. [PDF]
Cheng Y+5 more
europepmc +1 more source
A Bistable Assistive Device for Wireless Control of a Dysfunctional Bladder Under Minimal Stress
This paper presents a wireless system designed to restore bladder function in patients with an underactive bladder (UAB). The system features a multilayered structure, combining a pre‐shaped restoration layer with a spring‐based actuator. The system delivers 95–100% voiding efficiency within a 10‐s activation while ensuring minimal stress on the ...
Shujun Xiao+4 more
wiley +1 more source
Exploration of the optimal concentration of quercetin liposome nanoparticles for the treatment of liver damage. [PDF]
Yin N, Pang J, Liu X.
europepmc +1 more source
Correlative super‐resolution optical imaging of the ultrastructure of rat liver sinusoidal endothelial cells (LSECs) across a large field of view (FOV) with 3D structured illumination microscopy (3D‐SIM) and single‐molecule localization microscopy (SMLM), facilitated by a transparent polymer photonic waveguide chip, is presented.
Surjendu Bikash Dutta+9 more
wiley +1 more source
Recent advancement in prevention against hepatotoxicity, molecular mechanisms, and bioavailability of gallic acid, a natural phenolic compound: challenges and perspectives. [PDF]
Chen P, Zou F, Liu W.
europepmc +1 more source
Intrinsically Soft Implantable Electronics for Long‐term Biosensing Applications
Intrinsically soft implantable biosensors address the mechanical mismatch of conventional rigid implants, improving biocompatibility and stability. This review explores soft encapsulation matrices, stretchable conductors, implantation strategies, and chronic fixation techniques.
Su Hyeon Lee+5 more
wiley +1 more source
Drug-induced liver injury due to avacopan improved by mycophenolate mofetil: A case report. [PDF]
Yamashita R+4 more
europepmc +1 more source
This review examines recent advancements in multimodal bioelectronics, emphasizing machine learning integration to enhance functionality. The application of machine learning methodologies improving biosignal processing, device adaptability, and diagnostic accuracy is discussed to introduce Machine Learning enhanced bioelectronics as a pathway toward ...
Myoungjae Oh+11 more
wiley +1 more source
Machine Learning on Toxicogenomic Data Reveals a Strong Association Between the Induction of Drug-Metabolizing Enzymes and Centrilobular Hepatocyte Hypertrophy in Rats. [PDF]
Ikoma K+4 more
europepmc +1 more source