Results 231 to 240 of about 219,574 (288)

Targeting the PI3K/AKT signaling pathway: an important molecular mechanism of herbal medicine in the treatment of MASLD/MASH. [PDF]

Front Nutr
Jiang S, Zhai L, Shao Y, Sun F, Liu X.
europepmc   +1 more source

Changes in gut microbiota in <i>Gynura segetum</i>-induced liver injury. [PDF]

Front Microbiol
Zhang M, Liu L, Lian J, Zhang M, Yang X, Wang H.   +5 more
europepmc   +1 more source

Gut microbiota-metabolite interactions in drug-induced liver injury: mechanisms, biomarkers, and therapeutic perspectives. [PDF]

Front Cell Infect Microbiol
Mao X, Hu X, Fang J.
europepmc   +1 more source

Dynamic chemical labelling accurately quantifies microRNA-122 and reveals the presence of isomiRs that compromise PCR-based analysis in drug-induced liver injury

, 2019
Dear, James, López-Longarela, Barbara, Morrison, Emma, Tranter, John David, Ilyine, Hugh, Duffy, David, Diaz-Mochon, Juan   +6 more
openaire   +1 more source

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Ferroptosis: action and mechanism of chemical/drug-induced liver injury

Drug and Chemical Toxicology, 2023
Drug-induced liver injury (DILI) is characterized by hepatocyte injury, cholestasis injury, and mixed injury. The liver transplantation is required for serious clinical outcomes such as acute liver failure. Current studies have found that many mechanisms
Li Zeng, Xueli Jin, Qing-Ao Xiao, Wei Jiang, Shanshan Han, Jin Chao, Ding Zhang, Xuan Xia, Decheng Wang   +8 more
semanticscholar   +3 more sources

Morin: a promising hepatoprotective agent against drug and chemical-induced liver injury

Naunyn-Schmiedeberg's Archives of Pharmacology
A. Pandi, Nabendu Sen, Vanitha Manickam Kalappan, Vanita Lal   +3 more
semanticscholar   +2 more sources

A comprehensive review of Dynamic Chemical Labelling on Luminex xMAP technology: a journey towards Drug-Induced Liver Injury testing.

Analytical Methods, 2023
Drug-Induced Liver Injury (DILI) is a grave global adverse event that can result in fatal consequences, causing drug failures, market withdrawals, and regulatory warnings, leading to substantial financial losses.
Antonio Marín-Romero, Salvatore Pernagallo   +1 more
semanticscholar   +1 more source

Mechanisms of the hepatoprotective effects of tamoxifen against drug-induced and chemical-induced acute liver injuries

Toxicology and Applied Pharmacology, 2012
Although estrogen receptor (ER)α agonists, such as estradiol and ethinylestradiol (EE2), cause cholestasis in mice, they also reduce the degree of liver injury caused by hepatotoxicants as well as ischemia-reperfusion. The functional mechanisms of ERα have yet to be elucidated in drug-induced or chemical-induced liver injury.
Yukitaka, Yoshikawa, Taishi, Miyashita, Satonori, Higuchi, Koichi, Tsuneyama, Shinya, Endo, Tohru, Tsukui, Yasuyuki, Toyoda, Tatsuki, Fukami, Miki, Nakajima, Tsuyoshi, Yokoi   +9 more
openaire   +2 more sources