Results 141 to 150 of about 545,592 (346)

The Evaluation of Dark Chocolate-Elicited Emotions and Their Relation with Physico Chemical Attributes of Chocolate. [PDF]

Foods, 2021
Bartkiene E, Mockus E, Mozuriene E, Klementaviciute J, Monstaviciute E, Starkute V, Zavistanaviciute P, Zokaityte E, Cernauskas D, Klupsaite D.   +9 more
europepmc   +1 more source

Functional analysis of soil chemical attributes using Geographic Information Systems to assess nutrient deficiencies

, 2023
Manuella Vieira Barbosa Neto, Maria do Socorro Bezerra de Araújo, José Coelho de Araújo Filho, Cristiane Barbosa da Silva, Everardo Valadares de Sá Barretto Sampaio   +4 more
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Concurrent Effects of Drought and Heat Stresses on Physio-Chemical Attributes, Antioxidant Status and Kernel Quality Traits in Maize (Zea mays L.) Hybrids. [PDF]

Front Plant Sci, 2022
Yousaf MI, Riaz MW, Jiang Y, Yasir M, Aslam MZ, Hussain S, Sajid Shah SA, Shehzad A, Riasat G, Manzoor MA, Akhtar I.   +10 more
europepmc   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Analysis and evaluation in the production process and equipment area of the low-cost solar array project [PDF]

The attributes of the various metallization processes were investigated. It is shown that several metallization process sequences will lead to adequate metallization for large area, high performance solar cells at a metallization add on price in the ...
Goldman, H., Wolf, M.
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Biosolids in the establishment of herbaceous species and in chemical and microbiological attributes in soil impacted by coal mining

, 2021
Natália Caron Kitamura, Cledimar Rogério Lourenzi, Alcenir Cláudio Bueno, Antônio Lourenço Pinto, Cláudio Roberto Fonsêca Sousa Soares, Admir José Giachini   +5 more
openalex   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Integrated control of invasive alien plants in terrestrial ecosystems [PDF]

Effective management of invading alien plants in natural and semi-natural systems is imperative if we are to prevent enormous impacts. An integrated approach involving the combined use of a range of methods is usually necessary to control invasive alien ...
Higgins, Steven Ian, Richardson, Dave, van Wilgen, Brian   +2 more
core   +1 more source