Results 31 to 40 of about 8,059,342 (255)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Highly sensitive laser-induced fluorescence detector for algal identification by capillary electrophoresis

Talanta Open
To achieve rapid and efficient detection of algal cells, this study developed a high-sensitivity laser-induced fluorescence detector with dimensions of 14 × 5.7 × 2.8 cm3.
Chenyang Ding, Yuanhang Wang, Yong Zheng, Jiashan Lu, Guiqiu Wang, Xuhui Geng   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Undoing composition? [PDF]

, 2012
This piece is a contribution to a symposium on the relationship of literacy studies to composition studies. Three central foci of literacy studies have direct implications for composition studies: the shift from canonical to everyday texts, practices and
Luke, Allan
core  

Chemical composition of sediment core PSEE-19_sand

, 2003
Chemical composition of sediment core PSEE ...
Sergey L Nikiforov (7887959), Nikiforov, Sergey L   +1 more
core   +1 more source

CHEMICAL COMPOSITION OF ROOT CHICORY

Овощи России, 2019
The value of the root chicory is due to the unique chemical composition of its roots. Depending on the variety, place of growth and growing conditions of culture chicory roots contain 72.0-77.0% water, 1.0-1.2% protein, 0.1-0.3% fat, 1.0-6.0% sugar, 12.0-
O. M. Vyutnova, I. A. Novikova
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Investigation of physico-chemical characteristics of iron-containing technogenic raw materials in the conditions of JSC “AMT”

Metalurgija, 2023
The results of experiments conducted to determine the efficiency of the use of man-made waste, including largescale in volume among the waste of metallurgical production, melted films and sludge of the oxygen converter shop are presented.
M. Mukhametkhan, Ye. Mukhametkhan, G. Zhabalova, L. Kamkina   +3 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source