Results 71 to 80 of about 892,606 (308)

Impacts of local human activities on the Antarctic environment [PDF]

, 2008
We review the scientific literature, especially from the past decade, on the impacts of human activities on the Antarctic environment. A range of impacts has been identified at a variety of spatial and temporal scales.
Agnew, Agnew, Ainley, Baker, Ballance, Bargagli, Barrera-Oro, Brown, C.A. Moreno, Chen, Clarke, Clarke, Constable, Constable, Constable, Convey, Convey, Convey, Convey, Cooney, Croxall, Croxall, D.G. Ainley, de Leeuw, de Poorter, Delord, DeVries, Duhamel, Edwards, Fraser, Frenot, Gon, Greenslade, Greenslade, Greenslade, Gremmen, Gröndahl, Hansom, Hee, Hemmings, Hofman, Holmes, Hughes, Huiskes, I. Snape, J. Scott, Jones, Jouventin, K.A. Hughes, Kennicutt, Kerry, Knox, Kock, Kock, Kock, Kohnen, Laws, McDonald, Moreno, Morris, Muller-Schwarze, Naveen, Naveen, Nicol, Ohtani, Olech, Otley, P. Convey, Pauly, Pauly, Peter, Pfeiffer, Pfeiffer, Rounsevell, S. Pfeiffer, Salwicka, Sjoling, Sladen, Smith, Smith, Snape, Snape, Summerson, T. Tin, Tejedo, Thor, Trathan, Weimerskirch, Wheeler, Willock, Woehler, Z.L. Fleming   +91 more
core   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Sediment Quality in Puget Sound Year 3 - Southern Puget Sound [PDF]

, 2002
As a component of a three-year cooperative effort of the Washington State Department of Ecology and the National Oceanic and Atmospheric Administration, surficial sediment samples from 100 locations in southern Puget Sound were collected in 1999 to ...
Aasen, Sandra, Anderson, Jack W., Biedenbach, James, Carr, R. Scott, Dutch, Margaret, Hameedi, Jawed, Johnson, Tom, Long, Edward R., Magoon, Stuart, Mueller, Cornelia, Scott, K. John, Welch, Kathy   +11 more
core  

Quantitative-spatial assessment of soil contamination in S. Francisco de Assis due to mining activity of the Panasqueira mine (Portugal) [PDF]

, 2013
Through the years, mining and beneficiation processes produces large amounts of As-rich mine wastes laid up in huge tailings and open-air impoundments (Barroca Grande and Rio tailings) that are the main source of pollution in the surrounding area once ...
A Corrêa de Sá, A Kloke, A Tessier, AB McKenzie, Ana Rita Salgueiro, AW Rose, BFJ Manly, BM Chapman, C Reimann, Carla Candeias, CCME–Canadian Council of Ministers of the Environment, CG Lee, DC Adriano, DG Brookins, DK Nordstrom, DL Massart, E Deschamps, E Galán, Eduardo Ferreira da Silva, F Noronha, G Cavey, GMS Abrahim, H Nishida, H Wackernagel, Henrique Garcia Pereira, HO Son, HT Chon, JC Davis, JF Verner, JM Zhou, KM Ellickson, KM Witte, KW Kim, L Hakanson, M Benvenuti, M Radojevic, M Smith, MC Jung, MJ Greenacre, NF Gray, P Godin, P Ávila, Paula Freire Ávila, S Henin, SC Wong, WC Kelly, WH Liu, WX Liu, X-P Yan   +48 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Detection of chemical contaminants [PDF]

, 2018
With the financial support of Internal Security Fund Police Programme European Commission Directorate General Home Affairs. This project has been founded with support from the European Commission. This publication reflects the views only of the authors, and European Commission cannot be held responsible for any use which may be made of the information ...
Stela, Maksymilian, Ceremuga, Michał, Szyposzyńska, Monika, Spławska, Aleksandra, Mirosz, Danuta, Truszkowska, Katarzyna   +5 more
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Fermentation with Pectin Trans-Eliminase to Reduce Cadmium Levels in Nacional and CCN-51 Cocoa Bean Genotypes

Plants
Cocoa represents a crucial source of income in coastal regions of Ecuador, where the product is exported for the production of high-value chocolates.
Wiston Javier Morales-Rodriguez, Jaime Morante-Carriel, Mercedes Carranza-Patiño, Darko Ormaza-Vásquez, María Concepción Ayuso-Yuste, María Josefa Bernalte-García   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Assessment of Bacterial Accumulation and Environmental Factors in Sentinel Oysters and Estuarine Water Quality from the Phang Nga Estuary Area in Thailand. [PDF]

, 2018
This study characterized microbiological and chemical contamination of oyster meat and estuarine water in Phang Nga, Thailand. Pooled oyster meats (n = 144), estuarine waters (n = 96) and environmental parameters were collected from March, 2016 to ...
Atwill, Edward R, Chuanchuen, Rungtip, Jeamsripong, Saharuetai   +2 more
core   +2 more sources