Results 131 to 140 of about 2,016,153 (312)
Petri Net Model Predictive Control Method for Batch Chemical Systems
In order to address the problem of the real-time scheduling and control of batch chemical systems, this work proposes a model predictive control method based on Petri nets.
Shasha Sun +4 more
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Recent Advances in Reinforcement Learning for Chemical Process Control
This paper reviews the recent advancements of reinforcement learning (RL) for chemical process control. RL presents a systematic strategy in which the machine learning agent learns a policy of actions based on interactions with the environment.
Venkata Srikar Devarakonda +3 more
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
HortTechnologyBoxwood, valued at over $140.9 million annually in the United States, faces a significant threat from boxwood blight disease. This study evaluated 24 treatment combinations involving three fungicides (Daconil Weatherstik, Postiva, and F6123-1), a ...
Bhawana Ghimire +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Chemical emergencies overview [PDF]
The CDC has a key role in protecting the public's health in an emergency involving the release of a chemical that could harm people's health. This document provides information to help people be prepared to protect themselves during and after such an ...
core
Time-step volume-preserving control of chemical reactors
, 2007 We present a general control and optimization strategy based on time-step state space volume control. This is performed by maintaining the divergence of the system close to zero.
Zaldívar, José Manuel +1 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source