Results 151 to 160 of about 1,834,987 (265)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Potential of Essential Oils and Major EO Constituents in the Chemical Control of <i>Spodoptera frugiperda</i>. [PDF]

Plants (Basel)
Usseglio VL, Beato M, Dambolena JS, Zunino MP.   +3 more
europepmc   +1 more source

Response of faba bean to intercropping, biological and chemical control against broomrape and root rot diseases. [PDF]

Saudi J Biol Sci, 2022
El-Mehy AA, El-Gendy HM, Aioub AAA, Mahmoud SF, Abdel-Gawad S, Elesawy AE, Elnahal ASM.   +6 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Chemical control of colloidal self-assembly driven by the electrosolvation force. [PDF]

Nat Commun
Wang S, Walker-Gibbons R, Watkins B, Lin B, Krishnan M.   +4 more
europepmc   +1 more source

Dual electrochemical and chemical control in atom transfer radical polymerization with copper electrodes. [PDF]

Chem Sci, 2022
De Bon F, Lorandi F, Coelho JFJ, Serra AC, Matyjaszewski K, Isse AA.   +5 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Identification and Chemical Control of Stem Canker Pathogen of <i>Idesia polycarpa</i>. [PDF]

Plants (Basel)
Feng J, Yuan Q, Chen X, Fang L, Zhang T, Liu Z, Wang Y, Geng X, Cai Q, Li Z.   +9 more
europepmc   +1 more source

Effect of the combination of biological, chemical control and agronomic technique in integrated management pea root rot and its productivity. [PDF]

Sci Rep, 2022
Nazir N, Badri ZA, Bhat NA, Bhat FA, Sultan P, Bhat TA, Rather MA, Sakina A.   +7 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source