Results 141 to 150 of about 1,834,987 (265)

Efficacy of Biological and Chemical Control Agents against Heterobasidion Spore Infections of Norway Spruce and Scots Pine Stumps on Drained Peatland. [PDF]

J Fungi (Basel), 2023
Piri T, Saarinen M, Hamberg L, Hantula J, Gaitnieks T.   +4 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

High-Throughput Surface Modification of Ordered Mesoporous Alumina Enables Structural Stabilization and Selective Chemical Control. [PDF]

Nanomaterials (Basel)
Bindon S, Colburn TW, Dauskardt RH.
europepmc   +1 more source

An Evaluation of Cultural and Chemical Control Practices to Reduce Slug Damage in No-till Corn. [PDF]

Insects, 2022
Dively GP, Patton T.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Chemical Control of Protease Activity and Gene Expression Using a Biotin-Released Inhibitory Domain. [PDF]

ACS Synth Biol
Van Keuren AM, Simoes CT, Tucker CL.
europepmc   +1 more source

Effectiveness of autocidal gravid trapping and chemical control in altering abundance and age structure of Aedes albopictus. [PDF]

Pest Manag Sci, 2022
Figurskey AC, Hollingsworth B, Doyle MS, Reiskind MH.   +3 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Crude toxin production and chemical control of Boeremia exigua. [PDF]

Sci Rep
Zhang P, Zhang W, Wang S, Zhang H, Zhu M, Wu D, Sun Y, Zhang H.   +7 more
europepmc   +1 more source

Chemical control and insecticide resistance status of sand fly vectors worldwide. [PDF]

PLoS Negl Trop Dis, 2021
Balaska S, Fotakis EA, Chaskopoulou A, Vontas J.   +3 more
europepmc   +1 more source