Results 141 to 150 of about 4,378,664 (305)
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Chemical growth control of Chinese elm trees
A 2500 ppm MH30T spray applied in July appeared to give satisfactory growth control in Chinese elms the following year, at least up to the later part of June—and with less detrimental effects to the trees than other sprays tried.
W Hamilton, W Davis
doaj
Molecular Real-Time PCR Monitoring of Onion Fusarium Basal Rot Chemical Control. [PDF]
Dimant E, Degani O.
europepmc +1 more source
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Persistence of Abscisic Acid Analogs in Plants: Chemical Control of Plant Growth and Physiology. [PDF]
Nguyen CH, Yan D, Nambara E.
europepmc +1 more source
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Emerging technologies for the chemical control of root parasitic weeds. [PDF]
Kawada K +4 more
europepmc +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Chemical Control of Mosquitoes and the Pesticide Treadmill: A Case for Photosensitive Insecticides as Larvicides. [PDF]
Meier CJ, Rouhier MF, Hillyer JF.
europepmc +1 more source
Most of the diseases with which dentists must deal with are related to microbial plaque and bacterial infection. The mechanical removal of supra- and subgingival plaque by the patient and by the dentist respectively, is time consuming and exacting, furthermore it is not one hundred per cent successful. There has been extensive search for many years for
openaire +1 more source

