Results 31 to 40 of about 1,761,173 (265)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Chemical control: Mosquito resistance to insecticides

California Agriculture, 1980
California Agriculture - All ...
G Georghiou
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Wind erosion control with chemical sprays

California Agriculture, 1963
Soil stabilization for wind erosion control is now possible by using chemical sprays. More tests are needed to determine the optimum dilution and application rates but the amount of spray to apply depends basically upon whether the stabilized surface ...
J Letey, D Halsey, A Van Maren, W Richardson   +3 more
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

The crystal structure of 2-benzylsuccinic acid, C11H12O6 Z. Kristallogr. - New Cryst. Struct.

Zeitschrift für Kristallographie - New Crystal Structures
C11H12O4, orthorhombic, Pna21 (no. 33), a = 18.9628(4) Å, b = 5.58910(10) Å, c = 9.6527(2) Å, V = 1023.04(4) Å3, Z = 4, Rgt(F) = 0.0308, wRref(F2) = 0.0849, T = 297 K.
Zhang Caiyu, Wang Fengfeng, Chen Hua, Luan Lin, Hu Xiaowen, Liu Yang   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The crystal structure of bepotastine besilate, C27H31ClN2O6S

Zeitschrift für Kristallographie - New Crystal Structures
C27H31ClN2O6S, triclinic, P1 (no. 1), a = 8.0223(3) Å, b = 9.8143(3) Å, c = 10.2307(4) Å, α = 88.308(3)°, β = 69.000(3)°, γ = 65.970(3)°, V = 680.39(5) Å3, Z = 1, R gt(F) = 0.0406, wRref (F 2) = 0.1165, T = 297 K.
Wang Fengfeng, Luan Lin, Hu Xiaowen, Zhang Caiyu, Liu Yang   +4 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The crystal structure of 3-(7,8-dimethoxy-2-oxo-1,2,4,5-tetrahydro-3H-benzo[d]azepin-3-yl)-N-methylpropan-1-aminium chloride monohydrate, C16H27ClN2O4

Zeitschrift für Kristallographie - New Crystal Structures
C16H27ClN2O4, orthorhombic, Pbca (no. 61), a = 14.8507(3) Å, b = 7.75674(15) Å, c = 31.3294(5) Å, V = 3608.92(11) Å3, Z = 8, Rgt(F) = 0.0406, wRref(F2) = 0.1222, T = 297 K.
Wang Fengfeng, Hu Xiaowen, Zhang Caiyu, Luan Lin, Liu Yang   +4 more
doaj   +1 more source