Results 71 to 80 of about 1,834,987 (265)

Enhancing recombinant thaumatin production by Komagataella phaffii through cold atmospheric helium plasma jet

Scientific Reports
Cold atmospheric plasma is emerging as a non-thermal and non-invasive tool for influencing microbial metabolism by modifying bioreactor conditions.
Nivedita Parsekar, Simen Akkermans, Dmytro Kozak, Jan F. M. Van Impe   +3 more
doaj   +1 more source

Eficácia biológica de bifentrina aplicado em milho armazenado sob diferentes temperaturas Biological efficacy of applied bifenthrin in stored corn under different temperatures

Revista Brasileira de Engenharia Agrícola e Ambiental, 2005
Considerando-se as altas temperaturas nos graneleiros junto à esteira transportadora de grãos objetivou-se, neste trabalho, avaliar a influência da temperatura no momento da pulverização, sobre a eficácia biológica do bifentrina. Para isso, pulverizou-se
Marco A. G. Pimentel, Lêda R. D'Antonino Faroni, Raul N. C. Guedes, José R. Gonçalves, Carlos R. F. de Oliveira   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

The crystal structure of 2-aminobutanamide hydrochloride, C4H11ClN2O

Zeitschrift für Kristallographie - New Crystal Structures
C4H11ClN2O, monoclinic, P21/n (no. 14), a = 4.8097(2) Å, b = 19.4142(10) Å, c = 7.8686(4) Å, β = 94.399(4)°, V = 732.58(6) Å3, Z = 4, Rgt(F) = 0.0438, wRref(F2) = 0.1308, T = 297 K.
Luan Lin, Hu Xiaowen, Zhang Caiyu, Wang Fengfeng   +3 more
doaj   +1 more source

Resolving conformational polymorphism in disulfide-rich peptide drugs

Frontiers in Chemistry
Disulfide-rich peptide therapeutics often exhibit compact cystine knot-like architectures that endow them with high conformational rigidity, proteolytic stability, and target specificity.
Shaozhou Zhu, Yifeng Ge, Haiwei Huang, Mingzhe Xu   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

The crystal structure of (R)-2-aminobutanamide hydrochloride, C4H11ClN2O

Zeitschrift für Kristallographie - New Crystal Structures
C4H11ClN2O, orthorhombic, P212121 (no. 19), a = 4.9699(1) Å, b = 7.5867(2) Å, c = 17.3719(4) Å, V = 655.01(3) Å3, Z = 4, Rgt(F) = 0.0286, wRref(F2) = 0.0796, T = 200 K.
Wang Fengfeng, Luan Lin, Wang Youyou, Hu Xiaowen, Zhang Caiyu, Liu Yang   +5 more
doaj   +1 more source