Results 81 to 90 of about 2,016,153 (312)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Chemical master equation and Langevin regimes for a gene transcription model [PDF]
Gene transcription models must take account of intrinsic stochasticity. The Chemical Master Equation framework is based on modelling assumptions that are highly appropriate for this context, and the Stochastic Simulation Algorithm (also known as ...
Higham, Desmond J. +4 more
core +1 more source
The crystal structure of (2-butyl-benzofuran-3-yl)(4-hydroxy-3,5-diiodophenyl)methanone, C19H16I2O3
C19H16I2O3, triclinic, P1̄ (no. 2), a = 8.9049(1) Å, b = 9.1514(1) Å, c = 12.0282(2) Å, α = 101.511(1)°, β = 101.691(1)°, γ = 93.386(1)°, V = 935.49(2) Å3, Z = 2, Rgt(F) = 0.0454, wRref(F2) = 0.1289, T = 297 K.
Wang Fengfeng +4 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
The crystal structure of 3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-triene-7-carbonitrile, C11H11NO2
C11H11NO2, monoclinic, P21/n (no. 14), a = 8.5089(4) Å, b = 8.2786(4) Å, c = 14.4166(6) Å, β = 105.035(5)°, V = 980.77(8) Å3, Z = 4, Rgt(F) = 0.0505, wRref(F2) = 0.1391, T = 297 K.
Wang Fengfeng +4 more
doaj +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
The crystal structure of 4-bromo-2,6-dimethoxybenzaldehyde, C9H9BrO3
C9H9BrO3, monoclinic, C2/c (no. 15), a = 19.8576(5) Å, b = 4.1080(2) Å, c = 23.1284(8) Å, β = 94.983(3)°, V = 1879.57(12) Å3, Z = 8, Rgt(F) = 0.0416, wRref(F2) = 0.1155, T = 297 K.
Wang Fengfeng +4 more
doaj +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Control of chemical reaction in high-intensity laser field
The prospects of control chemical reaction in high-intensity laser field are talked about here, and some experimental and theoretical designs are reviewed and discussed ...
Lou, NQ, Sun, ZG, Cong, SL
core
C12H18ClNO2, orthorhombic, P212121 (no. 19), a = 5.2689(2) Å, b = 10.3289(7) Å, c = 24.629(3) Å, V = 1340.34(18) Å3, Z = 4, Rgt(F) = 0.0574, wRref(F2) = 0.1463, T = 297 K.
Wang Fengfeng +4 more
doaj +1 more source

