Results 71 to 80 of about 16,100,535 (247)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Chemical Modifications of Starch: Microwave Effect

International Journal of Polymer Science, 2015
This paper presents basic methods of starch chemical modification, the effect of microwave radiation on the modification process, and the physicochemical properties of starch.
Kamila Lewicka, Przemysław Siemion, Piotr Kurcok   +2 more
doaj   +1 more source

Numerical investigation of the mechano-electro-chemical effect of X100 buried pipelines with pre-existing corrosion defects. [PDF]

Heliyon, 2023
Mubarak G, Gadala I, Barsoum I, AlFantazi A.   +3 more
europepmc   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

The Physical Processes and Chemical Transformations of Third-Hand Smoke in Indoor Environments and Its Health Effects: A Review

Atmosphere
Tobacco smoke is an important pollutant that causes over 8 million deaths each year, of which, 1.3 million deaths are attributed to second-hand smoke. Third-hand smoke refers to the chemical emitted from smoking that remains in the air, dust, and on the ...
Yuyu Wang, Jianwei Gu
doaj   +1 more source

AI for predicting chemical-effect associations at the chemical universe level-deepFPlearn. [PDF]

Brief Bioinform, 2022
Schor J, Scheibe P, Bernt M, Busch W, Lai C, Hackermüller J.   +5 more
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Multiphasic bone-ligament-bone integrated scaffold enhances ligamentization and graft-bone integration after anterior cruciate ligament reconstruction

Bioactive Materials
The escalating prevalence of anterior cruciate ligament (ACL) injuries in sports necessitates innovative strategies for ACL reconstruction. In this study, we propose a multiphasic bone-ligament-bone (BLB) integrated scaffold as a potential solution.
Xianrui Xie, Jiangyu Cai, Dan Li, Yujie Chen, Chunhua Wang, Guige Hou, Thorsten Steinberg, Bernd Rolauffs, Mohamed EL-Newehy, Hany EL-Hamshary, Jia Jiang, Xiumei Mo, Jinzhong Zhao, Jinglei Wu   +13 more
doaj   +1 more source

Mechano-Chemical Effect of Gelatin- and HA-Based Hydrogels on Human Retinal Progenitor Cells. [PDF]

Gels, 2023
Dromel PC, Singh D, Alexander-Katz A, Kurisawa M, Spector M, Young M.   +5 more
europepmc   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source