Results 61 to 70 of about 20,829,679 (312)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Multilayer sandwich composite structures have significant applications in impact protection. In particular, they demonstrate superior protective performance when subjected to impacts from explosive fragment particle clusters.
Wei ZHENG +4 more
doaj +1 more source
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Chemical pollution of the aquatic environment is nowadays characterised by increasing levels of anthropogenic organic compounds at low concentrations and is recognised as one of the main drivers of the deteriorated ecological state of European ...
Fabian G. Weichert +6 more
doaj +1 more source
Chemical Synthesis and Characterization of Pd/SiO2: The Effect of Chemical Reagent
The size and shape distribution of metal nanoparticles (NPs) are important parameters that need to be tuned in order to achieve desired properties of materials for practical applications.
Aram L. Bugaev +8 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Chemical Modification of Kraft Lignin: Effect on Chemical and Thermal Properties
Esterified kraft lignins (KL) were prepared by reaction with maleic anhydride (MA), succinic anhydride (SA), and phthalic anhydride (PA) in acetone solutions.
Yao Chen +5 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
How can ultrasonic scouring of sheep’s wool chemically modify its surface?
Ultrasonic wool scouring has the potential to replace the traditional method using detergents and other additives. This study aims to investigate the effect of important parameters of an ultrasonic bath operating at 38 kHz frequency on the possible ...
Mária Porubská +2 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

