Results 61 to 70 of about 20,829,679 (312)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Research Progress on Dynamic Mechanical Response Characteristics of High-Velocity Particle Flow Impacting Multilayer Sandwich Composite Structures

open access: yesGaoya wuli xuebao
Multilayer sandwich composite structures have significant applications in impact protection. In particular, they demonstrate superior protective performance when subjected to impacts from explosive fragment particle clusters.
Wei ZHENG   +4 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Dataset on target chemical and bioassay analysis—Exploring contaminants of emerging concern in a low mountain river of central Germany

open access: yesData in Brief
Chemical pollution of the aquatic environment is nowadays characterised by increasing levels of anthropogenic organic compounds at low concentrations and is recognised as one of the main drivers of the deteriorated ecological state of European ...
Fabian G. Weichert   +6 more
doaj   +1 more source

Chemical Synthesis and Characterization of Pd/SiO2: The Effect of Chemical Reagent

open access: yesMetals, 2018
The size and shape distribution of metal nanoparticles (NPs) are important parameters that need to be tuned in order to achieve desired properties of materials for practical applications.
Aram L. Bugaev   +8 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Chemical Modification of Kraft Lignin: Effect on Chemical and Thermal Properties

open access: yesBioResources, 2014
Esterified kraft lignins (KL) were prepared by reaction with maleic anhydride (MA), succinic anhydride (SA), and phthalic anhydride (PA) in acetone solutions.
Yao Chen   +5 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

How can ultrasonic scouring of sheep’s wool chemically modify its surface?

open access: yesUltrasonics Sonochemistry
Ultrasonic wool scouring has the potential to replace the traditional method using detergents and other additives. This study aims to investigate the effect of important parameters of an ultrasonic bath operating at 38 kHz frequency on the possible ...
Mária Porubská   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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