Results 91 to 100 of about 2,520,715 (284)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A bio-based functional separator enables dendrite-free anodes in aqueous zinc-ion batteries

iScience
Summary: Aqueous zinc-ion batteries (AZIBs) have garnered considerable interest as potential solutions for large-scale energy storage systems, owing to their cost-effectiveness and high safety.
Han Zhang, Jinbo Li, Huaizheng Ren, Jianxin Wang, Yuxin Gong, Bo Wang, Dianlong Wang, Huakun Liu, Shixue Dou   +8 more
doaj   +1 more source

Imperative of Integrating Process Safety Education in Chemical Engineering Curricula. [PDF]

ACS Omega, 2023
Guerrero-Pérez J.
europepmc   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

New approaches in the engineering and characterization of macromolecular interfaces across the length scales: applications to hydrophobic and stimulus responsive polymers [PDF]

, 2007
The aim of the present Thesis is to enhance characterization and surface engineering approaches to test and control physico-chemical changes on modified hydrophobic (LDPE and PDMS) and stimulus-responsive (PFS) polymers across different length scales ...
Song, Jing
core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Mechanical Engineering: Medium-Sized Companies with Highest Savings Potential [PDF]

The German mechanical engineering industry, dominated by medium-sized companies, is greatly successful - both on the domestic and on the international market.
Alexander S. Kritikos, Alexander Schiersch   +1 more
core  

Water self-sufficiency with separate treatment of household rainwater and greywater [PDF]

, 2014
This paper is based on an academic work conducted by a group of students of the Engineering Project course within the Chemical Engineering Degree at the Engineering School of Barcelona. The objective of the exercise was to design a rainwater harvesting
García Blanch, Elisa, García Gisbert, Anna, Lloveras Macià, Joaquín, Planas Gisbert, María, Rodríguez Farre, Ariadna   +4 more
core  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Chemical Engineering Principles In A Freshman Engineering Course Using A Cogeneration Family [PDF]

, 2020
Robert Hesketh, C. Stewart Slater
openalex   +1 more source