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Chemical Evolution of Natural Product Structure. [PDF]
Natural products are the result of Nature’s exploration of biologically relevant chemical space through evolution and an invaluable source of bioactive small molecules for chemical biology and medicinal chemistry.
Grigalunas M, Brakmann S, Waldmann H.
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Pseudo Natural Products-Chemical Evolution of Natural Product Structure. [PDF]
Pseudo‐natural products (PNPs) combine natural product (NP) fragments in novel arrangements not accessible by current biosynthesis pathways. As such they can be regarded as non‐biogenic fusions of NP‐derived fragments.
Karageorgis G+4 more
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Autocatalytic Sets Arising in a Combinatorial Model of Chemical Evolution [PDF]
The idea that chemical evolution led to the origin of life is not new, but still leaves open the question of how exactly it could have led to a coherent and self-reproducing collective of molecules.
Wim Hordijk, Mike Steel, Stuart Kauffman
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The Informational Substrate of Chemical Evolution: Implications for Abiogenesis [PDF]
A key aspect of biological evolution is the capacity of living systems to process information, coded in deoxyribonucleic acid (DNA), and used to direct how the cell works.
Andrés de la Escosura
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Role of Mineral Surfaces in Prebiotic Chemical Evolution. In Silico Quantum Mechanical Studies. [PDF]
There is a consensus that the interaction of organic molecules with the surfaces of naturally-occurring minerals might have played a crucial role in chemical evolution and complexification in a prebiotic era.
Rimola A, Sodupe M, Ugliengo P.
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A recursive microfluidic platform to explore the emergence of chemical evolution [PDF]
We propose that a chemically agnostic approach to explore the origin of life, using an automated recursive platform based on droplet microfluidics, could be used to induce artificial chemical evolution by iterations of growth, speciation, selection, and ...
David Doran+4 more
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Cosmic Chemical Evolution [PDF]
ApJ(Letters) in press, 15 latex pages and 4 ...
Renyue Cen, Jeremiah P. Ostriker
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Stellar chemical evolution [PDF]
One of the major achievements of astrophysics has been the demonstration that most of the chemical elements have been synthesized in stars: nucleosynthesis calculations of homogeneous and inhomogeneous big bang cosmologies show that, in comparison with the most metal-poor stars currently known, essentially no elements heavier than B existed at the era ...
John E. Norris
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Primitive Photosynthetic Architectures Based on Self‐Organization and Chemical Evolution of Amino Acids and Metal Ions [PDF]
The emergence of light‐energy‐utilizing metabolism is likely to be a critical milestone in prebiotic chemistry and the origin of life. However, how the primitive pigment is spontaneously generated still remains unknown.
Kai Liu+4 more
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Retrocausality in Quantum Phenomena and Chemical Evolution
The interplay between retrocausality and the time-reversal symmetry of the dynamical law of quantum mechanics underscores the significance of the measurement dynamics with the use of indivisible and discrete quantum particles to be mediated.
Koichiro Matsuno
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