Results 131 to 140 of about 255,270 (305)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Supplemmentary material - GIB fractions chemical characterization

open access: yes, 2020
Chemical characterization before and after gastro-intestinal digestion.
openaire   +1 more source

Chemical nitrogen fractionation in dense molecular clouds

open access: yesMonthly Notices of the Royal Astronomical Society, 2018
21 pages, 3 ...
Loison, Jean-Christophe   +3 more
openaire   +3 more sources

Nitrogen superfractionation in dense cloud cores

open access: yes, 2008
We report new calculations of interstellar 15N fractionation. Previously, we have shown that large enhancements of 15N/14N can occur in cold, dense gas where CO is frozen out, but that the existence of an NH + N channel in the dissociative recombination ...
Alexander C. M. O'D.   +5 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

AN EVOLUTION FROM PRETREATMENT TO FRACTIONATION WILL ENABLE SUCCESSFUL DEVELOPMENT OF THE INTEGRATED BIOREFINERY

open access: yesBioResources, 2010
The current state of biorefinery development is focused almost entirely on the production of fuel ethanol. However, an ethanol-centric approach misses the crucial example set by the petrochemical industry.
Joseph J. Bozell
doaj  

Isolasi dan Identifikasi Senyawa Seskuiterpen dari Curcuma soloensis Val. (Temu Glenyeh)

open access: yesJurnal Kimia Valensi, 2018
Curcuma soloensis Val. is a family plant Zingiberaceae and is known as "temu gelnyeh". This plant has been used as a medicinal plant but has not been widely reported about its chemical components.
Soerya Dewi Marliyana   +3 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Seasonal trends of the stable nitrogen isotope ratio in particulate nitrogen compounds and their gaseous precursors in Akita, Japan

open access: yesTellus: Series B, Chemical and Physical Meteorology, 2019
Particulate matter (PM) can have adverse effects on human health. Moreover, because the mechanisms of PM formation and behavior in the atmosphere are notably complicated, to reduce PM concentrations effectively and meet environmental standards, source ...
Hiroto Kawashima
doaj   +1 more source

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