Results 81 to 90 of about 6,179,886 (326)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Pasture Recovery Period Affects Humic Substances and Oxidations of Organic Matter in Eastern Amazon

Agronomy
Land management practices that overlook soil limitations and potential have led to varying degrees of degradation. This study evaluates the carbon content in chemical and oxidisable soil fractions across different pasture recovery periods, comparing them
Carlos Augusto Rocha de Moraes Rego, Juan López de Herrera, Paulo Sérgio Rabello de Oliveira, Luciano Cavalcante Muniz, Jean Sérgio Rosset, Eloisa Mattei, Lucas da Silveira, Marinez Carpiski Sampaio, Marcos Gervasio Pereira, Karolline Rosa Cutrim Silva, Ismênia Ribeiro de Oliveira   +10 more
doaj   +1 more source

The 15N-enrichment in dark clouds and Solar System objects

, 2013
The line intensities of the fundamental rotational transitions of H13CN and HC15N were observed towards two prestellar cores, L183 and L1544, and lead to molecular isotopic ratios 140 6 14N/15N 6 250 and 140 6 14N/15N 6 360, respectively.
Bonal, Lydie, Faure, Alexandre, Hily-Blant, Pierre, Quirico, Eric   +3 more
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Clouds, Clumps, Cores & Comets - a Cosmic Chemical Connection?

, 2008
We discuss the connection between the chemistry of dense interstellar clouds and those characteristics of cometary matter that could be remnants of it. The chemical evolution observed to occur in molecular clouds is summarized and a model for dense core ...
Charnley, S. B., Rodgers, S. D.
core   +2 more sources

A general perspective of the characterization and quantification of nanoparticles: Imaging, spectroscopic, and separation techniques [PDF]

, 2014
This article gives an overview of the different techniques used to identify, characterize, and quantify engineered nanoparticles (ENPs). The state-of-the-art of the field is summarized, and the different characterization techniques have been grouped ...
Anderson de la LLana, S., Anderson, I.S., Capitán Vallvey, L. F., Cecchini, R., Costa Fernández, J.M., Domínguez Meister, Santiago, Lapresta Fernández, A., Marco, María Pilar, Moreno Bondi, M.C., Salinas Castillo, A., Sánchez López, J.C.   +10 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Chemical Leaching of Metals from Landfill's Fine Fraction

, 2020
Leaching of heavy metals (chromium, zinc, copper) from the fine fraction of the Torma landfill (Estonia) was investigated. The leaching kinetics studies have determined the dependence of some metal’s concentration on the leaching time. Metals were leached with Aqua Regia, distilled water and EDTA (Ethylenediaminetetraacetic acid); process was most ...
Balkauskaitė, E., Bučinskas, A., Ivanauskas, R., Kriipsalu, M., Denafas, G.   +4 more
openaire   +1 more source