Results 51 to 60 of about 8,109,255 (400)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Aligned Chemically Etched Silver Nanowire Monolayer as Surface-Enhanced Raman Scattering Substrates
Nanoscale Research Letters, 2017 Silver nanowires (AgNWs) were chemically etched to significantly increase the surface roughness and then self-assembled on the liquid/gas interfaces via the interfacial assembly method to obtain aligned chemically etched silver nanowire films.
Jianchao Wang +5 more
doaj +1 more source
Chemical industry supply chain optimisation using agent-based modelling [PDF]
, 2013 In this paper we present an application of Supply Chain Spread Sheet Simulator (SCSS) in a task dealing with chemical industry supply chain redesign and optimisation.
Dyntar, Jakub, Škvor, Jan
core +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
International Journal of Polymer Science, 2015 Preparation of urushiol derivatives was carried out in response to the drug industry’s increasing demand for new synthetic anticancer agents. Urushiol methylene acetal derivatives were synthesized in high yields by reaction of urushiol with methylene ...
Chengzhang Wang +6 more
doaj +1 more source
Polymer-Supported Raney Nickel Catalysts for Sustainable Reduction Reactions
Molecules, 2016 Green is the future of chemistry. Catalysts with high selectivity are the key to green chemistry. Polymer-supported Raney catalysts have been found to have outstanding performance in the clean preparation of some chemicals.
Haibin Jiang +4 more
doaj +1 more source
Journal of Saudi Chemical Society, 2023 In this work, we proposed a facile one-pot pyrolysis method to conveniently manufacture lignin-derived carbon materials with graded porous construction for use in supercapacitors.
Xiaohan Zhang +5 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
BioResources, 2015 The aim of this study was to separate antityrosinase compounds of the ethyl acetate fraction from Rhus verniciflua Stokes using medium pressure liquid chromatography.
Hongxia Chen +4 more
doaj +1 more source