Results 91 to 100 of about 367,263 (338)

Measuring chemical composition and particle cross-section of ultra-high energy cosmic rays by a ground radio array [PDF]

open access: yesarXiv, 2013
We present a technique to measure chemical composition and particle cross-section of ultra-high energy cosmic rays using radio data. We relate the geometry of the radio footprint on the ground to the depth of the extensive air shower maximum. We suggest to use the spectral information of the radio signal to improve the shower maximum reconstruction by ...
arxiv  

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Microglial reprogramming: a potential new frontier in enhancing immunotherapy for melanoma brain metastasis

open access: yesMolecular Oncology, EarlyView.
Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger   +2 more
wiley   +1 more source

Langmuir Monolayer Studies of Phosphatidylcholine Membranes with Naproxen on the Polysaccharide Subphase

open access: yesMolecules
Natural polysaccharides are biocompatible and biodegradable; therefore, they can be widely used in drug delivery, tissue engineering and wound healing. In this context, the interactions between polysaccharides, drugs and biological membranes are of great
Małgorzata Jurak   +2 more
doaj   +1 more source

Effect of β-PVDF Piezoelectric Transducers’ Positioning on the Acoustic Streaming Flows

open access: yesMicromachines, 2014
This paper reports the numerical and experimental analysis of the acoustic streaming effect in a fluidic domain. The actuation of a piezoelectric transducer generates acoustic waves that propagate to the fluids, generating pressure gradients that induce ...
Susana O. Catarino   +2 more
doaj   +1 more source

Spectrum synthesis for magnetic, chemically stratified stellar atmospheres [PDF]

open access: yesarXiv, 2007
Modern investigations of magnetic chemically peculiar stars reveal a variety of complex processes in their atmospheres. Realistic spectrum synthesis modelling of these objects has to take into account anomalous chemical composition, strong magnetic field and chemical stratification.
arxiv  

Relaxation Phenomena in a Bistable Chemical System

open access: yes, 1984
A theoretical investigation is presented of the relaxation dynamics of a simple model which gives a near-quantitative description of the iodate-excess arsenous acid systems (1). Near the hysteresis limits (K≳ K1, K≲ K2, K= input flow rate) and near the critical point K an exact expression is obtained for the nonlinear response to a sudden change of the
Dewel, Guy   +2 more
openaire   +3 more sources

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

open access: yesFEBS Open Bio, EarlyView.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia   +5 more
wiley   +1 more source

Establishment and biological characterization of radioresistant colorectal cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu   +10 more
wiley   +1 more source

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