Results 91 to 100 of about 5,494,217 (358)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Mini-grand canonical ensemble: chemical potential in the solvation shell

open access: yes, 2017
Quantifying the statistics of occupancy of solvent molecules in the vicinity of solutes is central to our understanding of solvation phenomena. Number fluctuations in small `solvation shells' around solutes cannot be described within the macroscopic ...
Asthagiri, Dilip   +3 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Chemical reacting flows [PDF]

open access: yes
Future aerospace propulsion concepts involve the combination of liquid or gaseous fuels in a highly turbulent internal air stream. Accurate predictive computer codes which can simulate the fluid mechanics, chemistry, and turbulence combustion interaction
Mularz, Edward J., Sockol, Peter M.
core   +1 more source

Resonant and crossover phenomena in a multiband superconductor tuning the chemical potential near a band edge

open access: yes, 2010
Resonances in the superconducting properties, in a regime of crossover from BCS to mixed Bose-Fermi superconductivity, are investigated in a two-band superconductor where the chemical potential is tuned near the band edge of the second mini-band ...
A. Bianconi   +13 more
core   +1 more source

Mean Drop Diameter in a Rotating Sieved Disc Contactor

open access: yesInternational Journal of Technology, 2015
A correlation has been proposed for mean drop diameter in a Rotating Sieved Disc Contactor (RSDC) considering drops break up, as well as drops coalescence with static holdup in the case of no mass transfer.
Fatemeh Behzad   +3 more
doaj   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

open access: yesMolecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal   +4 more
wiley   +1 more source

Maze solvers demystified and some other thoughts

open access: yes, 2017
There is a growing interest towards implementation of maze solving in spatially-extended physical, chemical and living systems. Several reports of prototypes attracted great publicity, e.g.
A Adamatzky   +25 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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