Results 61 to 70 of about 1,191,147 (335)

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

open access: yesMolecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien   +7 more
wiley   +1 more source

Quasi-quantized Hall response in bulk InAs

open access: yesScientific Reports, 2022
The quasi-quantized Hall effect (QQHE) is the three-dimensional (3D) counterpart of the integer quantum Hall effect (QHE), exhibited only by two-dimensional (2D) electron systems.
R. Wawrzyńczak   +5 more
doaj   +1 more source

Impossibility of a perpetuum mobile based on the nano-confinement effect on chemical equilibrium [PDF]

open access: yesarXiv, 2010
Impossibility of a perpetuum mobile based on the nano-confinement effect on chemical equilibrium is considered.
arxiv  

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Hard magnet topological semimetals in XPt3 compounds with the harmony of Berry curvature

open access: yesCommunications Physics, 2021
Topological magnetic semimetals can realise large intrinsic anomalous Hall effects using the characteristics of their electronic band structure and Berry curvature.
Anastasios Markou   +8 more
doaj   +1 more source

Protein Structure Determination Using Chemical Shifts [PDF]

open access: yesarXiv, 2014
In this PhD thesis, a novel method to determine protein structures using chemical shifts is presented.
arxiv  

Ordering chemical graphs by Sombor indices and its applications [PDF]

open access: yesarXiv, 2021
Topological indices are a class of numerical invariants that predict certain physical and chemical properties of molecules. Recently, two novel topological indices, named as Sombor index and reduced Sombor index, were introduced by Gutman, defined as $$SO(G)=\sum_{uv\in E(G)}\sqrt{d_{G}^{2}(u)+d_{G}^{2}(v)},$$ $$SO_{red}(G)=\sum_{uv\in E(G)}\sqrt{(d_{G}
arxiv  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Nickel-catalyzed divergent Mizoroki–Heck reaction of 1,3-dienes

open access: yesNature Communications, 2023
Developing efficient strategies to realize divergent arylation of dienes has been a longstanding synthetic challenge. Herein, a nickel-catalyzed divergent Mizoroki–Heck reaction of 1,3-dienes has been demonstrated through the modification of ligands and ...
Wei-Song Zhang   +6 more
doaj   +1 more source

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