Results 61 to 70 of about 5,646,274 (337)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Probabilistic Physics-integrated Neural Differentiable Modeling for Isothermal Chemical Vapor Infiltration Process [PDF]

, 2023
Deepak Akhare, Zeping Chen, Richard Gulotty, Tengfei Luo, Jianxun Wang   +4 more
openalex   +1 more source

BBN and the Primordial Abundances

, 2005
The relic abundances of the light elements synthesized during the first few minutes of the evolution of the Universe provide unique probes of cosmology and the building blocks for stellar and galactic chemical evolution, while also enabling constraints ...
C. Chiappini, D. Kirkman, D.N. Spergel, G. Steigman, G. Steigman, I. Iben, J. Lequeux, J. Melendez, J.A. Thorburn, J.N. Bahcall, J.P. Kneller, K.A. Olive, L. Randall, M. Kawasaki, M.H. Pinsonneault, P. Bonifacio, R.T. Rood, S. Cassisi, S.G. Ryan, S.M. Viegas, T.M. Bania, V. Barger   +21 more
core   +2 more sources

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Detection of Gaseous Plumes using Basis Vectors

Sensors, 2009
Detecting and identifying weak gaseous plumes using thermal imaging data is complicated by many factors. There are several methods currently being used to detect plumes.
Lawrence Chilton, Stephen Walsh
doaj   +1 more source

Enhanced molecular yield from a cryogenic buffer gas beam source via excited state chemistry

New Journal of Physics, 2020
We use narrow-band laser excitation of Yb atoms to substantially enhance the brightness of a cold beam of YbOH, a polyatomic molecule with high sensitivity to physics beyond the standard model (BSM).
Arian Jadbabaie, Nickolas H Pilgram, Jacek Kłos, Svetlana Kotochigova, Nicholas R Hutzler   +4 more
doaj   +1 more source

Creating enzymes and self-sufficient cells for biosynthesis of the non-natural cofactor nicotinamide cytosine dinucleotide

Nature Communications, 2021
Nicotinamide cytosine dinucleotide is an NAD mimic that can be used to mediate redox reactions. Here the authors design an NCD synthetase for the intracellular production of NCD.
Xueying Wang, Yanbin Feng, Xiaojia Guo, Qian Wang, Siyang Ning, Qing Li, Junting Wang, Lei Wang, Zongbao K. Zhao   +8 more
doaj   +1 more source

JINA-NuGrid Galactic Chemical Evolution Pipeline

, 2016
Galactic chemical evolution is a topic that involves nuclear physics, stellar evolution, galaxy evolution, observation, and cosmology. Continuous communication and feedback between these fields is a key component in improving our understanding of how ...
Côté, Benoit, Fryer, Chris L., Herwig, Falk, Jones, Samuel, O'Shea, Brian W., Pignatari, Marco, Ritter, Christian, Silvia, Devin   +7 more
core   +1 more source

Locating transition states using double-ended classical trajectories [PDF]

, 1994
In this paper we present a method for locating transition states and higher-order saddles on potential energy surfaces using double-ended classical trajectories.
A. Matro, D. L. Freeman, Doll J. D., J. D. Doll   +3 more
core   +5 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source