Results 101 to 110 of about 3,070,839 (358)

STAT3 expression is reduced in cardiac pericytes in HFpEF and its loss reduces cellular adhesion and induces pericyte senescence

FEBS Letters, EarlyView.
Heart failure with preserved ejection fraction (HFpEF) accounts for half of the heart failure cases. It is characterised by microvascular dysfunction, associated with reduced pericyte coverage and diminished STAT3 expression in pericytes. Loss of STAT3 impairs pericyte adhesion, promotes senescence, and activates a pro‐fibrotic gene program.
Leah Rebecca Vanicek, Ariane Fischer, Mariano Ruz Jurado, Anita Tamiato, Tara Procida‐Kowalski, Jochen Wilhelm, Dennis Hecker, Maximilian Merten, Felicitas Escher, Badder Kattih, Valentina Puntmann, David John, Marcel H. Schulz, Eike Nagel, Stefanie Dimmeler, Guillermo Luxán   +15 more
wiley   +1 more source

FRECKLL: Full and Reduced Exoplanet Chemical Kinetics DistiLLed

The Astrophysical Journal
We introduce a new Python 1D chemical kinetic code, Full and Reduced Exoplanet Chemical Kinetics distiLLed ( FRECKLL ), to evolve large chemical networks efficiently.
Ahmed Faris Al-Refaie, Olivia Venot, Quentin Changeat, Billy Edwards   +3 more
doaj   +1 more source

The Pisa Stellar Evolution Data Base for low-mass stars

, 2012
The last decade showed an impressive observational effort from the photometric and spectroscopic point of view for ancient stellar clusters in our Galaxy and beyond.
Degl'Innocenti, S., Dell'Omodarme, M., Moroni, P. G. Prada, Valle, G.   +3 more
core   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

AutoTemplate: enhancing chemical reaction datasets for machine learning applications in organic chemistry

Journal of Cheminformatics
This paper presents AutoTemplate, an innovative data preprocessing protocol, addressing the crucial need for high-quality chemical reaction datasets in the realm of machine learning applications in organic chemistry.
Lung-Yi Chen, Yi-Pei Li
doaj   +1 more source

Automatic Extension of a Semi-Detailed Synthetic Fuel Reaction Mechanism

Energies
To identify promising sustainable fuels, e.g., to select novel synthetic fuels with the greatest impact on minimizing global warming, new methods for rapid and economical technical fuel assessment are urgently needed.
Marleen Schmidt, Celina Anne Kathrin Eberl, Sascha Jacobs, Torsten Methling, Andreas Huber, Markus Köhler   +5 more
doaj   +1 more source

Kaemika app, Integrating protocols and chemical simulation [PDF]

arXiv, 2020
Kaemika is an app available on the four major app stores. It provides deterministic and stochastic simulation, supporting natural chemical notation enhanced with recursive and conditional generation of chemical reaction networks. It has a liquid-handling protocol sublanguage compiled to a virtual digital microfluidic device.
arxiv  

Development of an Uncertainty Quantification Predictive Chemical Reaction Model for Syngas Combustion

, 2017
An automated data-centric infrastructure, Process Informatics Model (PrIMe), was applied to validation and optimization of a syngas combustion model. The Bound-to-Bound Data Collaboration (B2BDC) module of PrIMe was employed to discover the limits of ...
N. Slavinskaya, M. Abbasi, J. Starcke, R. Whitside, A. Mirzayeva, Uwe Riedel, Wenyu Li, James Oreluk, Arun Hegde, A. Packard, M. Frenklach, G. Gerasimov, O. Shatalov   +12 more
semanticscholar   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Reactivity of OH and CH3OH between 22 and 64 K: Modelling the gas phase production of CH3O in Barnard 1b

, 2016
In the last years, ultra-low temperature chemical kinetic experiments have demonstrated that some gas-phase reactions are much faster than previously thought.
Agundez, M., Albaladejo, J., Antinolo, M., Ballesteros, B., Canosa, A., Cernicharo, J., Dib, G. El, Jimenez, E.   +7 more
core   +3 more sources