Results 91 to 100 of about 777,399 (277)
Structural bifurcation analysis in chemical reaction networks
Physical Review E, 2018 29 pages, 12 figures.
Okada, Takashi +2 more
openaire +4 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Turing Instability of Brusselator in the Reaction-Diffusion Network
Complexity, 2020 Turing instability constitutes a universal paradigm for the spontaneous generation of spatially organized patterns, especially in a chemical reaction. In this paper, we investigated the pattern dynamics of Brusselator from the view of complex networks ...
Yansu Ji, Jianwei Shen
doaj +1 more source
Precision and Sensitivity in Detailed-Balance Reaction Networks
, 2016 We study two specific measures of quality of chemical reaction networks, Precision and Sensitivity. The two measures arise in the study of sensory adaptation, in which the reaction network is viewed as an input-output system. Given a step change in input,
de Greef, Tom F. A. +3 more
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Statistical measure of dispersity in complex weighted networks of low temperature plasma chemistry
Journal of Physics: ComplexityA chemical reaction system is frequently complex when its molecular species are excited by high-energy external sources. Here we examine molecular (SiH _4 ) plasma chemistry in which high-energy electrons dissociate, decompose and polymerize many ...
Kota Hamano +4 more
doaj +1 more source
Stability Analysis for a Class of Non-Weakly Reversible Chemical Reaction Networks
SICE Journal of Control, Measurement, and System Integration, 2018 We consider ordinary differential equations (ODEs) that describe the time evolution of the concentrations of species in chemical reaction networks (CRNs).
Hirokazu Komatsu, Hiroyuki Nakajima
doaj +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Nature CommunicationsMetabolite annotation in untargeted metabolomics remains challenging due to the vast structural diversity of metabolites. Network-based approaches have emerged as powerful strategies, particularly for annotating metabolites lacking chemical standards ...
Haosong Zhang +3 more
doaj +1 more source