Results 61 to 70 of about 669,188 (305)
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Modeling the Impact of Moderate External UV Irradiation on Disk Chemistry
The Astrophysical JournalThe chemistry within a protoplanetary disk is greatly affected by external radiation from the local stellar environment. Previous work has focused on extreme radiation fields, representative of the center of something like the Orion Nebula Cluster ...
Rachel E. Gross, L. Ilsedore Cleeves
doaj +1 more source
Ain Shams Engineering Journal, 2017 The underlying system models of time series prediction are complex and not known a priori, hence, accurate and unbiased estimation cannot be always achieved using well known linear techniques.
S.C. Nayak, B.B. Misra, H.S. Behera
doaj +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
International Journal of Molecular Sciences, 2011 The formation of a self-sustaining autocatalytic chemical network is a necessary but not sufficient condition for the origin of life. The question of whether such a network could form “by chance” within a sufficiently complex suite of molecules and ...
W. Hordijk, S. Kauffman, M. Steel
semanticscholar +1 more source
Automatic Inference of Graph Transformation Rules Using the Cyclic Nature of Chemical Reactions
, 2016 Graph transformation systems have the potential to be realistic models of chemistry, provided a comprehensive collection of reaction rules can be extracted from the body of chemical knowledge. A first key step for rule learning is the computation of atom-
Flamm, Christoph +3 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Energies, 2021 Deep learning has recently emerged as a successful approach to produce accurate subgrid-scale (SGS) models for Large Eddy Simulations (LES) in combustion.
Victor Xing +3 more
doaj +1 more source
A detailed balanced reaction network is sufficient but not necessary for its Markov chain to be detailed balanced [PDF]
, 2013 Certain chemical reaction networks (CRNs) when modeled as a deterministic dynamical system taken with mass-action kinetics have the property of reaction network detailed balance (RNDB) which is achieved by imposing network-related constraints on the ...
Badal Joshi
semanticscholar +1 more source
On the Ionisation Fraction in Protoplanetary Disks II: The Effect of Turbulent Mixing on Gas--phase Chemistry [PDF]
, 2005 We calculate the ionisation fraction in protostellar disk models using two different gas-phase chemical networks, and examine the effect of turbulent mixing by modelling the diffusion of chemical species vertically through the disk.
Balbus +26 more
core +4 more sources