Results 41 to 50 of about 508,394 (292)

Evolutionary origin of power-laws in Biochemical Reaction Network; embedding abundance distribution into topology

open access: yes, 2005
The evolutionary origin of universal statistics in biochemical reaction network is studied, to explain the power-law distribution of reaction links and the power-law distributions of chemical abundances. Using cell models with catalytic reaction network,
Chikara Furusawa   +3 more
core   +1 more source

A global convergence result for processive multisite phosphorylation systems [PDF]

open access: yes, 2014
Multisite phosphorylation plays an important role in intracellular signaling. There has been much recent work aimed at understanding the dynamics of such systems when the phosphorylation/dephosphorylation mechanism is distributive, that is, when the ...
Conradi, Carsten, Shiu, Anne
core   +1 more source

PREDICTION OF REACTION CONDITIONS BY DEEP LEARNING TECHNIQUES [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2020
Subject of Research. The paper presents a study of prediction method for various properties of reactions, such as the type of reaction, suitable groups of solvents, catalysts for the reaction.
Vladimir B. Moskalev, Evgeniy O. Putin
doaj  

Automatic Inference of Graph Transformation Rules Using the Cyclic Nature of Chemical Reactions

open access: yes, 2016
Graph transformation systems have the potential to be realistic models of chemistry, provided a comprehensive collection of reaction rules can be extracted from the body of chemical knowledge. A first key step for rule learning is the computation of atom-
Flamm, Christoph   +3 more
core   +1 more source

Modeling dynamics of chemical reaction networks using electrical analogs: Application to autocatalytic reactions

open access: yesChemical Engineering Journal Advances, 2022
Modeling complex chemical reaction networks has inspired a considerable body of research and a variety of approaches to modeling nonlinear pathways are being developed. Here, a general methodology is formulated to convert an arbitrary reaction network into its equivalent electrical analog.
Sarang S. Nath, John Villadsen
openaire   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Modeling the Impact of Moderate External UV Irradiation on Disk Chemistry

open access: yesThe Astrophysical Journal
The chemistry within a protoplanetary disk is greatly affected by external radiation from the local stellar environment. Previous work has focused on extreme radiation fields, representative of the center of something like the Orion Nebula Cluster ...
Rachel E. Gross, L. Ilsedore Cleeves
doaj   +1 more source

Stochastic theory of large-scale enzyme-reaction networks: Finite copy number corrections to rate equation models

open access: yes, 2010
Chemical reactions inside cells occur in compartment volumes in the range of atto- to femtolitres. Physiological concentrations realized in such small volumes imply low copy numbers of interacting molecules with the consequence of considerable ...
Alberts B.   +6 more
core   +1 more source

Generic Strategies for Chemical Space Exploration [PDF]

open access: yes, 2014
Computational approaches to exploring "chemical universes", i.e., very large sets, potentially infinite sets of compounds that can be constructed by a prescribed collection of reaction mechanisms, in practice suffer from a combinatorial explosion.
Andersen, Jakob L.   +3 more
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

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