Results 61 to 70 of about 447,849 (263)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Hypergraph Laplace Operators for Chemical Reaction Networks
, 2018 We generalize the normalized combinatorial Laplace operator for graphs by defining two Laplace operators for hypergraphs that can be useful in the study of chemical reaction networks. We also investigate some properties of their spectra.Comment: 23 pages,
Jost, Jürgen, Mulas, Raffaella
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Chemical master versus chemical langevin for first-order reaction networks [PDF]
, 2008 Markov jump processes are widely used to model interacting species in circumstances where discreteness and stochasticity are relevant. Such models have been particularly successful in computational cell biology, and in this case, the interactions are ...
Higham, Desmond J., Khanin, Raya
core +1 more source
Deterministic function computation with chemical reaction networks [PDF]
Natural Computing, 2012 fixed errors in previous ...
Chen, Ho-Lin +2 more
openaire +6 more sources
Information thermodynamics for deterministic chemical reaction networks
The Journal of Chemical Physics, 2022 Information thermodynamics relates the rate of change of mutual information between two interacting subsystems to their thermodynamics when the joined system is described by a bipartite stochastic dynamics satisfying local detailed balance. Here, we expand the scope of information thermodynamics to deterministic bipartite chemical reaction networks ...
Emanuele Penocchio +2 more
openaire +5 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The Design of 2DOF IMC-PID Controller in Biochemical Reaction Networks
Applied Sciences, 2023 DNA molecules can be adopted to design biomolecular control circuits that can effectively control biochemical reaction processes. However, the leak reaction in actual biochemical reactions causes a significant uncertainty for reactions.
Yang Li, Hui Lv, Xing’an Wang
doaj +1 more source
On the multistationarity of chemical reaction networks
, 2019 We present a new conjecture about a necessary condition that a (bio)chemical network has to satisfy for it to exhibit multistationarity. According to a Theorem of Feliu and Wiuf [27, 12], the conjecture is known for strictly monotonic kinetics.
Kaufman, Marcelle, Soulé, Christophe
core +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source