Results 131 to 140 of about 3,463,529 (362)
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
Chemical production on Mars using in situ propellant production technology [PDF]
In situ propellant production (ISPP) was examined in terms of its applicability to a manned Mars mission. Production of oxygen from Martian atmosphere was used as the baseline system for ISPP technology assessment.
Ash, Robert L.
core +1 more source
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Feedback Mechanism of Chemical System from the Viewpoint of Information Technology [PDF]
Motoyosi Sugita
openalex +1 more source
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
Technology-enhanced learning influence on chemical literacy: A systematic review
Chemical literacy is essential to address socio-scientific issues arising today. Technology plays a key role in increasing students’ chemical literacy. Understanding how technology improves chemical literacy can help teachers choose appropriate learning ...
Ananta Ardyansyah, Sri Rahayu
doaj +1 more source
NASA's Chemical Transfer Propulsion Program for Pathfinder [PDF]
Pathfinder is a research and technology project, with specific deliverables, initiated by the National Aeronautics and Space Administration (NASA) which will strengthen the technology base of the United States civil space program in preparation for ...
Berkopec, Frank D. +2 more
core +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
CHEMICAL SURFACE TREATMENTS FOR URANIUM AND THEIR APPLICATION TO URANIUM TECHNOLOGY
Jenny Gore +4 more
openalex +2 more sources
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source

