Characterization of tautomeric forms of anti-cancer drug gemcitabine and their interconversion upon mechano-chemical treatment, using ATR-FTIR spectroscopy and complementary methods. [PDF]
J Pharm Biomed Anal, 2023 Henry B, Samokhvalov A.
europepmc +1 more source
Molecular Oncology, EarlyView.Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande +11 more
wiley +1 more source
Inducing apoptosis using chemical treatment and acidic pH, and detecting it using the Annexin V flow cytometric assay. [PDF]
PLoS One, 2022 Worsley CM, Veale RB, Mayne ES.
europepmc +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Nanostructure and Morphology of the Surface as Well as Micromechanical and Sclerometric Properties of Al2O3 Layers Subjected to Thermo-Chemical Treatment. [PDF]
Materials (Basel), 2022 Bara M +3 more
europepmc +1 more source
Cloud formation in giant planets
, 2007 We calculate the formation of dust clouds in atmospheres of giant gas-planets. The chemical structure and the evolution of the grain size distribution in the dust cloud layer is discussed based on a consistent treatment of seed formation, growth ...
Helling, Christiane
core
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source
A new animal product free defined medium for 2D and 3D culturing of normal and cancer cells to study cell proliferation and migration as well as dose response to chemical treatment. [PDF]
Toxicol Rep, 2023 Rafnsdóttir ÓB +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang +8 more
wiley +1 more source
Chemical Treatment of Bio-Derived Industrial Waste Filled Recycled Low-Density Polyethylene: A Comparative Evaluation. [PDF]
Polymers (Basel), 2021 Sider I, Nassar MMA.
europepmc +1 more source