Results 51 to 60 of about 207,787 (293)

Monitoring Chemical Pollution in Europe’s Seas: Programmes, practices and priorities for research [PDF]

, 2011
This report has been produced by the Marine Board Working Group on Existing and Emerging Chemical Pollutants (WGPOL) first convened in 2008 and tasked to examine the assessment and monitoring of existing and emerging chemicals in the European marine and ...
Albaigés, J., Bakke, T., Bebianno, M.J., Calewaert, J.-B., Camphuysen, C.J., Cronin, M., de Leeuw, J., Gabrielsen, G., Hutchinson, T., Hylland, K., Janssen, C., Jansson, B., Jenssen, B.M., McDonough, N., Roose, P., Schulz-Bull, D., Szefer, P., Webster, L.   +17 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Computational material flow analysis for thousands of chemicals of emerging concern in European waters [PDF]

Journal of Hazardous Materials, 2020
Journal of hazardous materials 397, 122655 (2020). doi:10.1016/j.jhazmat.2020.122655 special issue: "SI: Micropollutants in water / Edited by Sungpyo Kim, Sung Kyu Maeng, Jiangyong Hu, Shane Snyder, Despo Fatta-Kassinos"
Jos van Gils, Leo Posthuma, Ian T. Cousins, Werner Brack, Rolf Altenburger, Hans Baveco, Andreas Focks, Janek Greskowiak, Ralph Kühne, Stela Kutsarova, Claudia Lindim, Arjen Markus, Dik van de Meent, John Munthe, Rudy Schueder, Gerrit Schüürmann, Jaroslav Slobodnik, Dick de Zwart, Annemarie van Wezel   +18 more
openaire   +7 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Innovative analytical methodologies for characterizing chemical exposure with a view to next-generation risk assessment

Environment International
The chemical burden on the environment and human population is increasing. Consequently, regulatory risk assessment must keep pace to manage, reduce, and prevent adverse impacts on human and environmental health associated with hazardous chemicals ...
Žiga Tkalec, Jean-Philippe Antignac, Nicole Bandow, Frederic M. Béen, Lidia Belova, Jos Bessems, Bruno Le Bizec, Werner Brack, German Cano-Sancho, Jade Chaker, Adrian Covaci, Nicolas Creusot, Arthur David, Laurent Debrauwer, Gaud Dervilly, Radu Corneliu Duca, Valérie Fessard, Joan O. Grimalt, Thierry Guerin, Baninia Habchi, Helge Hecht, Juliane Hollender, Emilien L. Jamin, Jana Klánová, Tina Kosjek, Martin Krauss, Marja Lamoree, Gwenaelle Lavison-Bompard, Jeroen Meijer, Ruth Moeller, Hans Mol, Sophie Mompelat, An Van Nieuwenhuyse, Herbert Oberacher, Julien Parinet, Christof Van Poucke, Robert Roškar, Anne Togola, Jurij Trontelj, Elliott J. Price   +39 more
doaj   +1 more source

The role of mycotoxins in the human exposome: Application of mycotoxin biomarkers in exposome-health studies [PDF]

, 2018
Mycotoxins are secondary metabolites produced by fungi that may contaminate different foods intended for human consumption, resulting in a widespread exposure worldwide. The novel exposome paradigm has the ambition to decipher the different environmental
Cano Sancho, German, Marín Sillué, Sònia, Ramos Girona, Antonio J., Sanchís Almenar, Vicente   +3 more
core   +4 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

The emerging protocol: An integrated reliable and effective regime [PDF]

, 1999
Ye
Dando, Malcolm R., Pearson, Graham S.
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source