Results 141 to 150 of about 139,194 (301)

MicroRNA-451a in Colorectal Cancer Detection: Analytical and Preliminary Clinical Validation of a PCR-Free Chemiluminescent Assay [PDF]

Bahareh Soleimanpour, Mavys Tabraue-Chávez, Rosario Maria Sanchez-Martin, Juan José Guardia-Monteagudo, Veronica Tisato, Donato Gemmati, Giulio Ferrero, Alessio Naccarati, Barbara Pardini, Juan Diaz Mochon, Salvatore Pernagallo   +10 more
openalex   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

A Novel Hemizygous <i>ANOS1</i> Variant in a Patient With Kallmann Syndrome and Type 2 Diabetes Mellitus: A Case Report. [PDF]

Case Rep Endocrinol
Qin S, Zhang Y, Chen Y, Chen W, Ni Y, Zhong J.   +5 more
europepmc   +1 more source

Conditionally Significant eQTL and TWAS Analyses Identify MsRD26 as a Major Candidate Positive Regulator of Salt Tolerance in Medicago sativa L

Advanced Science, EarlyView.
Salt stress significantly impacts plant growth. Through population transcriptome, eQTL and TWAS analyses, we identified several candidate genes potentially associated with salt stress response. Functional assays suggested that some of these genes may contribute to salt tolerance.
Lin Chen, Yuqi Zhang, Xinyue Ma, Jinpeng Bi, Fei He, Li Zhao, Haiyue Lei, Zhengqin Xiao, Xue Wang, Tiejun Zhang, Ruicai Long, Junmei Kang, Qingchuan Yang   +12 more
wiley   +1 more source

Evaluation of a new non-competitive chemiluminescent immunoassay for 25-OH vitamin D measurement

Jinqing Zhong, Binning Huang, Aihua Lin, Geng Wu, Lili Zhang, Xiaowei Yu, Shun Zhuang, Daying Zheng, Huangxing Chen, Zhongying Zhang   +9 more
openalex   +1 more source

Genome‐Wide and Multi‐Omics Analysis Identified DNA‐Interacting Circular RNA circFOXK2 as MLL1 Regulator for Histone H3K4 Methylation in Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
Circular RNA circFOXK2 is frequently upregulated in pancreatic ductal adenocarcinoma to promote tumor heterogeneity, growth, and metastasis. Through circRNA‐DNA interaction at different genomic locations, circFOXK2 removes the PPIE inhibitory effects on MLL1 for gene‐activating H3K4 methylation of the oncogenes.
Chi Hin Wong, Jessica Jazmin Peña‐Paladines, Sum Yin Valerie Leung, Ka‐Fai To, Kenneth Siu Ho Chok, Yangchao Chen   +5 more
wiley   +1 more source

Assessing high-throughput surrogate assays for real-world HPV16- and HPV18-specific vaccine immune monitoring: a comparison of PBNA, cCLIA, and IgG. [PDF]

Front Immunol
Mao W, Yuan M, Fang Z, Zha R, Ye Y, Cai L, Wang L, Huang R, Luo S, Guo C, Liao C.   +10 more
europepmc   +1 more source

EP300‐Mediated MTF1‐K218 Lactylation Buffers AR‐Driven Copper Overload to Suppress Cuproptosis in Castration‐Resistant Prostate Cancer

Advanced Science, EarlyView.
Androgen receptor (AR) drives copper accumulation in prostate cancer while inducing MTF1 to buffer copper toxicity. EP300‐mediated lactylation of MTF1 at K218 promotes its nuclear translocation and metallothionein expression, sequestering cytosolic copper and preventing mitochondrial cuproptosis.
Kai Li, Yong Wei, Yongshan Li, Yuxiang Dong, Jiancheng Lv, Mingzhi Yuan, Ao Shen, Fuyang Liu, Yetao Zhang, Youjian Li, Ruixi Yu, Yang Liu, Tong Zhao, Jun Wang, Kai Zhou, Zongyao Fan, Manning Wang, Jun Xu, Mulong Du, Min Gu, Bing Yao, Qingyi Zhu   +21 more
wiley   +1 more source

Comparative Diagnostic Yield of Rapid Immunoassay-Based Tests and Nucleic Acid Testing for Transfusion-Transmissible Infections in a Tertiary Care Setting. [PDF]

Cureus
Singh DK, Singh R, Singh A, Tiwari V, Shukla S, Kumar G, Kumar M.   +6 more
europepmc   +1 more source

A Dual-Activatable Direct NIR-II Chemiluminescent Probe for High-Contrast Bioimaging In Vivo

Ling Li, Hongyan Yang, Xinyi Zhang, Yuxin Ren, Yajie Long, Qin Yin, Yanli Tang   +6 more
openalex   +1 more source