Results 151 to 160 of about 139,194 (301)

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

Advanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu, Xuan Lu, Yuquan Wang, Haihua Ji, Ying Zhang, Yiqun Wan, Hao Wan   +6 more
wiley   +1 more source

Quantification of Phosphorylated Tau Protein in Alzheimer's Disease Patients' Fluids With Electrolyte-Gated Organic Transistor Biosensors. [PDF]

Adv Healthc Mater
Berto M, Manco Urbina PA, Paradisi A, Sensi M, Iacovino N, Carbone C, Bedin R, Pinti M, Biscarini F, Zamboni G, Bortolotti CA.   +10 more
europepmc   +1 more source

Machine learning-assisted paper-based chemiluminescent biosensing platform for rapid detection of hydrogen peroxide contaminant in milk

Jitendra B. Zalke, Vani Kaushik, Chirag M. Singhal, Madhusudan B. Kulkarni, Manish L. Bhaiyya   +4 more
openalex   +1 more source

P53 - ECE_1519 - Impacts of the use of LC–MS/MS-equivalent chemiluminescent enzyme immunoassay-measured plasma aldosterone concentration in the diagnostic process of unilateral primary aldosteronism [PDF]

Shoichiro Izawa, Kazuhisa Matsumoto, Kanako Kadowaki, Toshifumi Nakamura, Norio Wada, Takuyuki Katabami, Yoichi Nozato, Ryuji Okamoto, Takamasa Ichijo, Daisuke Taura, Masanori Murakami, Miki Kakutani, Takashi Yoneda, Minemori Watanabe, Yutaka Takahashi, Shintaro Okamura, Katsutoshi Takahashi, Hiroki Kobayashi, Mitsuhide Naruse, Kenichi Yokota, Masakatsu Sone   +20 more
openalex   +1 more source

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

Advanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li, Nana Zhang, Zexin Bian, Baobao Geng, Liyun Cao, Peipei Liu, Zengming Li, Yan Zhao, Jun Tan   +8 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Electronegatively substituted adamantyl units accelerate chemiexcitation of 1,2-dioxetane luminophores while preserving chemical stability. [PDF]

Chem Sci
Leirikh T, Naama N, Wang D, Ge L, Ihssen J, Hupfeld M, Baran PS, Shabat D.   +7 more
europepmc   +1 more source

A Novel Chemiluminescent Immunoassay for Urinary LAM Detection Improves Tuberculosis Diagnosis in HIV Cohorts [PDF]

Yu Li, J L Lou, Hongjuan Wei, Limei Sun, Yanhua Yu, Yanwei Hu   +5 more
openalex   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

A Fully Automated Chemiluminescent Immunoassay for Component-Resolved Diagnosis of Pollen Allergy: Validation of Six CHORUS CLIA Assays [PDF]

Helena Cerutti, Simone Bianciardi, Giulia Barberini, Claudia Soldatini, Alessandra Cartocci, Tommaso Bandini, Giulia Tesi, Alessandra Brogi   +7 more
openalex   +1 more source