Results 131 to 140 of about 86,655 (290)

Strengthening STD Screening Programs: Comprehensive Evaluation of High-Throughput Immunoassays for HIV and Syphilis Detection

Microorganisms
Fourth-generation immunoassays are widely used for HIV and syphilis screening; however, false-reactive results may increase confirmatory testing and operational burden in high-throughput laboratories.
Ahmed Ismail, Shaden Abunasser, Israa M. Salameh, Mazen Najib Abouassali, Manal Elshaikh, Ibrahim Wissam Karimeh, Mohammed Abdelfatah Ibrahim, Mutaz Mohamed Ali, Ibrahim Al Shaar, Parveen Banu Nizamuddin, Salma Younes, Hadi M. Yassine, Laith J. Abu-Raddad, Nadin Younes, Gheyath K. Nasrallah   +14 more
doaj   +1 more source

Rapid and Efficient Affinity Isolation of Engineered Extracellular Vesicles Encapsulating Functional Proteins via Internal Twin‐Strep Tetraspanin Tagging

Small, EarlyView.
Structure‐guided internal twin‐Strep tagging of the tetraspanins CD63 or CD9 enables rapid and efficient antibody‐free affinity isolation of engineered extracellular vesicles (EVs) using Strep technology while allowing luminal protein loading. The approach removes over 96% of contaminants, separates tagged EVs from coexisting viral particles, and ...
Minh‐Tu Pham, Jona Benjamin Krohn, Janis Meyer, Christian Ritter, Martin Schneider, Dominic Helm, Dario Frey, Kleopatra Rapti, Uta Haselmann‐Weiss, Elif Toprak, Viet Loan Dao Thi, Florian Leuschner, Dirk Grimm, Karl Rohr, Ralf Bartenschlager   +14 more
wiley   +1 more source

Subgroup analysis of the included studies for GC.

, 2015
Note: AUC, area under the summary receiver operating characteristic curve; DOR, diagnostic odds ratio; RIA, radio-immunity assay; ELISA, enzyme-linked immunosorbent assay; CLIA, chemiluminescent immunoassay; L-TIA, latex-enhanced turbidimetric ...
Chao Yan (150844), Wei-ming Kang (595176), Shu-bo Tian (595174), Ya-kai Huang (824293), Jian-chun Yu (595175), Xin Ye (208347), Zhi-qiang Ma (595177)   +6 more
core   +1 more source

Electron‐Transfer Engineered Biointerface With Detonation Nanodiamonds for Next‐Generation Cortisol Electrochemical Immunoassay

Small, EarlyView.
Screen‐printed carbon electrode biointerface featuring detonation nanodiamond layer with the sp2/sp3 carbon interface that optimizes charge transfer and enables covalent immobilization of cortisol antibodies. The designed electrochemical sensor provides high selectivity, stability and rapid cortisol detection also from saliva samples.
Chakavak Esmaeili, Jaroslav Kuliček, Markéta Šlapal Bařinková, Bohuslav Rezek   +3 more
wiley   +1 more source

Engineering Carbon Nanotube Quantum Well Defects With Recognition Tripeptides for Optical Detection of Extracellular Vesicles in Plasma

Small, EarlyView.
A three‐residue peptide bioconjugated onto a carbon nanotube quantum defect turns the near‐infrared emission of quantum defects into a reporter of integrins on intact extracellular vesicles, directly in human plasma. The sensor reveals that healthy fibroblast vesicles carry as much RGD‐binding integrin as cancer‐derived ones, an adhesion‐associated ...
In‐Jun Hwang, Junhee Kim, Aarti Patel, Leilei Zhang, Jacob Miller, Stanislav Piletsky, Cassandra L. Clift, Colin Hisey, YongJoo Kim, Mijin Kim   +9 more
wiley   +1 more source

Immunosensing for detection of protein biomarkers /

, 2017
Includes index.Includes bibliographical references and index.Online resource, title from PDF title page (EBSCO, viewed June 6, 2017).Introduction -- Signal amplification for immunosensing -- Electrochemical immunosensing -- Functional nanoprobes for ...
Yan, Feng,author., Ju, Huangxian,author., Lai, Guosong,author.   +2 more
core  

Synergistic Toxicity of Low‐Concentration Metal Mixture on Male Rats: Reproductive, Renal, and Hepatic Effects

Environmental Toxicology, EarlyView.
ABSTRACT Mining plays a crucial role in economic development, but improper management can lead to severe environmental degradation. Particularly for iron ore, mining generates vast amounts of tailings often stored in unstable dams. This study aims to investigate the toxicological impacts of environmentally relevant concentrations of metals mixture ...
Kalinka Helóra Gomes de Almeida, Thalita Tofanin Sargiani D'Assumpção, Ana Priscila Gomes Silva, Carolina Rocha Moreira de Oliveira, Tailisi Hoppe Trevizani, Rubens Cesar Lopes Figueira, Lucas Buruaem Moreira, Juliana Elaine Perobelli   +7 more
wiley   +1 more source

Deficiency of high‐molecular‐weight von Willebrand factor mitigates thrombo‐complement injury in an LPS‐induced TMA‐like mouse model

VIEW, EarlyView.
Reduction of high‐molecular‐weight von Willebrand factor disrupts the platelet–complement amplification loop, attenuating microvascular thrombosis, complement deposition, endothelial injury, and organ damage in complement‐mediated thrombotic microangiopathy.
Yang Li, Chihao Zhang, Xiaoqian Xu, Sicong Wang, Xiaofan Hu, Junjie Yao, Xi Wu, Difeng Zhu, Qian Liang, Yeling Lu, Yu Liu, Guanqun Xu, Jiakuan Zhou, Qiulan Ding, Wenman Wu, Ya Li, Jing Dai, Xuefeng Wang   +17 more
wiley   +1 more source

Improving tumor marker comparability: A case series on harmonizing carbohydrate antigen 19‐9 and carbohydrate antigen 15‐3 measurements across diverse measurement systems

VIEW, EarlyView.
CA19‐9 and CA15‐3 measurements from seven contemporary immunoassay systems were compared using 464 and 499 native serum samples, respectively. Inter‐system correlations were higher for CA15‐3 than for CA19‐9, and only a limited number of systems met biological variation‐derived bias criteria.
Jia Li, Xiaoying Lou, Zongdan Wang, Mengdi Wu, Jing Zhang, Huishuang Gao, Meng Li, Bing Wu, Dongmei Ma, Kuo Zhang, Wei Cui   +10 more
wiley   +1 more source

Development of chemiluminescent methods for explosives detection

, 2009
The present work was finalised to develop chemiluminescent assays more sensitive and easy to use than the analytical methods currently in use to detect traces of TNT (2,4,6-trinitrotoluene), TATP (Triacetone triperoxide) and HMTD (Hexamethylene ...
FERRI, ELIDA NORA, M. J. Moreno, GIROTTI, STEFANO, CAPUTO, PASQUALE, S. A. Eremin, A. Montoya, G. Guarnieri, MAIOLINI, ELISABETTA, M. D’Elia   +8 more
core   +1 more source