Results 141 to 150 of about 86,655 (290)

Diagnostic value of plasma TFF3‐centered combined biomarker panel in early gastrointestinal cancer

open access: yesVIEW, EarlyView.
In this study, a retrospective cohort was established, including gastrointestinal cancer, non‐GI cancer, and healthy controls. TFF3, CEA, and gastric function indicators were detected. TFF3 showed significantly better diagnostic performance compared with conventional gastrointestinal indicators in gastric cancer, and compared with CEA in ...
Yizhou Huang   +7 more
wiley   +1 more source

Living Together, Loving Apart: Health, Sexuality and Relationships in Middle‐Aged and Older Men in Europe

open access: yesAndrology, EarlyView.
ABSTRACT Background Over time, family structures have grown more complex, diversifying adult relationships. While research has compared marital, cohabiting and living apart together relationships based on quality and health, less is known about their sexual dynamics.
Clotilde Sparano   +16 more
wiley   +1 more source

Sex Steroids Measurement by Mass Spectrometry in Hypogonadal Men in a Real‐World Setting: Serum Estradiol (E2) and E2 to Total Testosterone Ratio Do Not Differ Between Patients With Klinefelter Syndrome and Non‐Klinefelter Syndrome Hypogonadism

open access: yesAndrology, EarlyView.
ABSTRACT Background Traditionally, Klinefelter syndrome (KS) was considered a clinical condition associated with hyperestrogenism. Aim To compare circulating sex steroids, particularly estrogens, in a cohort of KS and non‐KS hypogonadal men. Materials and Methods A cohort of hypogonadal men, treated and untreated, was prospectively enrolled in a real ...
Daniele Renda Livraghi   +8 more
wiley   +1 more source

Development of chemiluminescent microparticle immunoassay for quantitative determination of dehydroepiandrosterone sulfate [PDF]

open access: yes, 2015
目的研制硫酸脱氢表雄酮化学发光免疫定量检测试剂。方法利用硫酸脱氢表雄酮人工完全抗原免疫小鼠,通过杂交瘤技术制备特异性抗硫酸脱氢表雄酮单克隆抗体,采用竞争抑制法建立硫酸脱氢表雄酮化学发光免疫定量检测试剂。结果筛选获得了27株稳定分泌抗硫酸脱氢表雄酮的单克隆抗体细胞株,建立了化学发光微粒子免疫法定量测定硫酸脱氢表雄酮的试剂盒雏形,与雅培公司的硫酸脱氢表雄酮定量检测试剂在检测临床标本上的相关系数r达0.99以上。结论本研究为国产化硫酸脱氢表雄酮化学发光微粒子免疫法定量测定试剂盒的研发奠定了基础 ...
黄明聪   +6 more
core  

Prevalence of Spermatozoa in the Ejaculate of Adolescents With Klinefelter Syndrome: Implications for Fertility Counseling

open access: yesAndrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is the most common genetic cause of male infertility and is associated with nonobstructive azoospermia. Advances in surgical sperm retrieval techniques have enabled biological fatherhood in a subset of men with KS.
Cecilie N. Larsen   +5 more
wiley   +1 more source

Father–Son Comparison of Reproductive Traits

open access: yesAndrology, EarlyView.
ABSTRACT Background Little is known about the relative contribution of genetic and environmental factors on male reproductive function. Objectives We studied in a cross‐sectional setting, whether testicular function and genital size correlate in father–son pairs.
Heidi Elamo   +9 more
wiley   +1 more source

Optimal calibration in immunoassay and inference on the coefficient of variation [PDF]

open access: yes, 2008
This thesis examines and develops statistical methods for design and analysis with applications in immunoassay and other analytical techniques. In immunoassay, concentrations of components in clinical samples are measured using antibodies.
Forkman, Johannes
core  

Marginal Changes in Semen Quality Over Three Decades (1996‒2022) Among 8320 Men in the Danish Young Men Study (DYMS): Cohort Profile and Trends

open access: yesAndrology, EarlyView.
ABSTRACT Background Since the 1990s, declining sperm counts and increasing testicular cancer rates have raised worldwide concern about male reproductive health, including in Denmark. This prompted a prospective population‐based study with annual surveillance of semen quality.
Lærke Priskorn   +13 more
wiley   +1 more source

Hypogonadism in Cisgender Men Living With HIV: Prevalence, Clinical and Metabolic Features

open access: yesAndrology, EarlyView.
ABSTRACT Background Hypogonadism is frequently observed in men living with human immunodeficiency virus (HIV), although its prevalence, etiology, and predictors remain incompletely understood. Objective To evaluate the prevalence of hypogonadism and its association with metabolic factors in men living with HIV (MLWH), on stable antiretroviral therapy ...
Felipe Augusto Azevedo Leao   +8 more
wiley   +1 more source

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