Results 41 to 50 of about 11,492,440 (323)

Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]

, 2017
Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin, Amento, Edward P, Kong, Raymond, Liu, David, Lundry, Jason, Madasamy, Shanmugavel, Robinson, J Paul, Wu, Alan HB   +7 more
core   +1 more source

Assessment of Coverage and Quality of Selected Clinical Chemistry Tests among Medical Laboratories of Health Facilities in Jimma Zone, South West Ethiopia

Journal of Tropical Medicine, 2019
Background. Medical laboratories play essential roles in measurement of analyte in clinical sample for the diagnosis and monitoring of diseases. Thus, data generated from the laboratory have to be reliable for which strict quality assurance is maintained.
Aklilu Getachew, Waqtola Cheneke, Yaregal Asres, Shiferaw Bekele, Estifanos Kebede   +4 more
doaj   +1 more source

Big Data in Laboratory Medicine—FAIR Quality for AI?

Diagnostics, 2022
Laboratory medicine is a digital science. Every large hospital produces a wealth of data each day—from simple numerical results from, e.g., sodium measurements to highly complex output of “-omics” analyses, as well as quality control results and metadata.
Tobias Ueli Blatter, Harald Witte, Christos Theodoros Nakas, Alexander Benedikt Leichtle   +3 more
doaj   +1 more source

Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors in clinical trials for cancer immunotherapy

Journal of Hematology & Oncology, 2021
Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme enzyme that catalyzes the oxidation of L -tryptophan. Functionally, IDO1 has played a pivotal role in cancer immune escape via catalyzing the initial step of the kynurenine pathway, and overexpression of ...
Kai Tang, Ya-hong Wu, Yihui Song, Bin Yu
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Synthetic cannabinoid use in a case series of patients with psychosis presenting to acute psychiatric settings : Clinical presentation and management issues [PDF]

, 2018
Background: Novel Psychoactive Substances (NPS) are a heterogeneous class of synthetic molecules including synthetic cannabinoid receptor agonists (SCRAs). Psychosis is associated with SCRAs use.
Bonaccorso, Stefania, Ducci, Giuseppe, Ferracuti, Stefano, Jamal, Leila, Metastasio, Antonio, Ricciardi, Angelo, Rujully, Naasir Ud Dinn, Schifano, Fabrizio, Stewart, Neil, Theleritis, Christos   +9 more
core   +3 more sources

Total Clinical Chemistry Laboratory Errors and Evaluation of the Analytical Quality Control Using Sigma Metric for Routine Clinical Chemistry Tests

Journal of Multidisciplinary Healthcare, 2021
Mulugeta Teshome,1 Abebaw Worede,2 Daniel Asmelash2 1Department of Medical Laboratory, Dessie Comprehensive Specialized Hospital, Dessie, Ethiopia; 2Department of Clinical Chemistry, School of Biomedical and Laboratory Sciences, College of Medicine and ...
Teshome M, Worede A, Asmelash D
doaj  

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Hematology and clinical biochemistry reference intervals for companion pigs using the ADVIA 2120 and Cobas c501 [PDF]

PeerJ
Background The majority of published reference intervals for hematology and clinical biochemistry in pigs are generated from a sample group that is demographically different from companion pigs, and as such may not be transferable.
Deanna M. W. Schaefer, Ricardo Videla, Joe S. Smith, Pierre-Yves Mulon, Bente Flatland, Xiaojuan Zhu   +5 more
doaj   +2 more sources