Results 51 to 60 of about 556,392 (291)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Pre-Analytical Considerations in Clinical Chemistry

Journal of Associated Medical Sciences, 2015
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Sheshadri Narayanan
doaj  

Clinical Chemistry and Autoverification: A Path Less Traversed [PDF]

Indian Journal of Medical Biochemistry
Aims and background: Autoverification (AV) is an application of artificial intelligence that uses computer-based algorithmically established rules for release of patient reports. This allows effective time management, prevents probable laboratory errors,
Rashmi Rasi Datta, Anurag Bansal
doaj   +1 more source

Community based reference interval of selected clinical chemistry parameters among apparently healthy Adolescents in Mekelle City, Tigrai, Northern Ethiopia.

PLoS ONE, 2020
BACKGROUND:Locally established clinical laboratory reference intervals (RIs) are required to interpret laboratory test results for screening, diagnosis and prognosis.
Getachew Belay, Gebreyohanes Teklehaymanot, Gebreslassie Gebremariam, Kelali Kaleaye, Hagos Haileslasie, Gebremedhin Gebremichail, Brhane Tesfanchal, Getachew Kahsu, Brhane Berhe, Kebede Tesfay, Lemlem Legesse, Ataklti Gebretsadik, Mistire Wolde, Aster Tsegaye   +13 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Accuracy in Clinical Chemistry

Clinical Chemistry, 1971
Abstract Improved accuracy of clinical laboratory measurements requires a broad range concept of quality control. Items considered include standardization, precision, specificity, recovery studies, interlaboratory comparisons, and long-range stability of laboratory performance.
openaire   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Advances in clinical chemistry patient-based real-time quality control (PBRTQC)

, 2023
Patient-Based Real-Time Quality Control involves monitoring an assay using patient samples rather than external material. If the patient population does not change, then a shift in the long-term assay population results represents the introduction of a ...
Katayev, A, Bietenbeck, A, Loh, TP, Badrick, T, Cervinski, MA, van Rossum, HH   +5 more
core   +1 more source

Clinical chemistry laboratory errors at St. Paul’s Hospital Millennium Medical College (SPHMMC), Addis Ababa, Ethiopia

BMC Research Notes, 2018
Objective This study was aimed to determine the magnitude of errors in clinical chemistry laboratory tests at different phases of the assay of clinical chemistry laboratory unit.
Hirut Tadesse, Kassu Desta, Samuel Kinde, Fatuma Hassen, Addisu Gize   +4 more
doaj   +1 more source