Results 41 to 50 of about 556,392 (291)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Profil Kimia Klinik Darah Sapi Bali (BLOOD CLINICAL CHEMISTRY PROFILES OF THE BALI CATTLE)

open access: yesJurnal Veteriner, 2013
For the evaluation of clinical tests in veterinary laboratories a reference basis of normal values ofclinically healthy farm animals is essential. It is well known that variables such as breed, age and sex havean influence on many blood parameters.
Anak Agung Sagung Kendran   +4 more
doaj  

Agarose gel electrophoresis: Applications in clinical chemistry [PDF]

open access: yesJournal of Medical Biochemistry, 2010
Agarose gel electrophoresis is a well established technique routinely used in clinical laboratories for screening protein abnormalities in various biological fluids (serum, urine, CSF).
Giot Jean-Francois
doaj  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Reference data of clinical chemistry, haematology and blood coagulation parameters in juvenile cynomolgus monkeys (Macaca fascicularis)

open access: yesVeterinární Medicína, 2012
Juvenile cynomolgus monkeys are valuable models for studying human diseases. Reference data of clinical chemistry, haematology and blood coagulation parameters of juvenile cynomolgus monkeys are very important for clinical diagnosis and conducting ...
H. Wang   +4 more
doaj   +1 more source

Analysis of the sex-specific variability of blood parameters in data sets of the Mouse Phenome Database

open access: yesBMC Research Notes, 2021
Objective The use of mice as animal models in biomedical research allows the standardization of genetic background and environmental conditions, which both affect phenotypic variability.
Bernhard Aigner
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Population-based pediatric reference intervals for general clinical chemistry analytes on the Abbott Architect ci8200 instrument

open access: yes, 2012
Background: Reference intervals are crucial decision-making tools aiding clinicians in differentiating between healthy and diseased populations. However, for children such values often are lacking or incomplete.
Aldrimer, Mattias   +6 more
core   +1 more source

Blood chemistry values in Thai patients receiving a check-up at Songklanagarind Hospital in the year 2004

open access: yesJournal of Health Science and Medical Research (JHSMR), 2006
Objective: To analyze and evaluate clinical chemistry blood values and study the incidence of low and high level values of Thais receiving a check-up at Songklanagarind Hospital in the year 2004. Meterial and Methods: Data comprising sex, age and results
P Chusongsang, B Wilirat
doaj  

Intracellular Clinical Chemistry

open access: yesClinical Chemistry, 1972
Abstract The plasma compartment, on which almost all routine analyses in clinical chemistry are performed, occupies only a small part of the body, most of which consists of cells. For most components the intracellular and extracellular compartments have a different composition in health, and change differently in disease.
openaire   +2 more sources

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