Results 121 to 130 of about 226,935 (353)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Making Redox Tangible: Physical Models in Electrochemistry Education

Education Sciences
This study addresses the persistent challenges that students face in understanding redox reactions, particularly the link between symbolic and particulate representations in electrochemistry. The purpose was to explore whether physical modeling with clay
Karina Adbo, Gunilla Akesson-Nilsson
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Learning Engagement in Reaction Kinetics: A Three-Dimensional Analysis in an Integrated Islamic Senior High School

JTK (Jurnal Tadris Kimiya)
Education plays a vital role in promoting students’ academic success, particularly in subjects that involve abstract and complex concepts such as reaction rates in chemistry.
Erlina Erlina, Aimi Zulaika, Rachmat Sahputra, Supriatno Salam   +3 more
doaj   +1 more source

Teaching of Undergraduate Chemistry Education Courses Through Information and Communication Technology Integration [PDF]

, 2019
Florence Obiageli Ezeudu, Florence O. Attah, Stephen Chinedu Nwafor   +2 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Didactic sequence to teach laboratory techniques in organic chemistry: analysis of terpenes in common medicines

Educación Química
This work presents a didactic sequence (DS) for teaching key laboratory techniques—continuous and discontinuous extraction, vacuum and atmospheric distillation, steam extraction, and thin-layer chromatography (TLC)—to first-year organic chemistry ...
Brenda de Moraes Cordeiro, Carlos Magno Rocha Ribeiro   +1 more
doaj   +1 more source

THE USE OF INTERACTIVE MODELING IN THE TEACHING OF CHEMISTRY IN HIGHER EDUCATION INSTITUTIONS

, 2022
O.V. Anichkina, O.Yu. Avdieieva
openalex   +1 more source

Forensic Chemistry Education [PDF]

Analytical Chemistry, 2005
openaire   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source