Results 131 to 140 of about 1,016,132 (353)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Contextual Socio-Scientific Issues and Education for Sustainable Development (SSI-ESD) Climate Change Module: Improving Chemical Literacy and Environmental Awareness among High School Students in Ketapang, Indonesia

Jurnal Kependidikan
This study investigates the effectiveness of a contextual Socio-Scientific Issues and Education for Sustainable Development (SSI-ESD) learning module on climate change in enhancing students’ chemical literacy and environmental awareness.
Restyani Ramadanty, Sri Handayani, Siska Widiana Putri   +2 more
doaj   +1 more source

Using collaborative CoRe design in chemistry education to promote effective partnerships between associate and student teachers [PDF]

, 2011
This article is a follow-up to my paper published in 2010 (Hume, 2010). In that paper I reported on the use of Content Representations (CoRes) in a chemistry education course to give student teachers insights into the professional knowledge of ...
Hume, Anne Christine
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Exploring Chemistry in Virtual Reality: A Comparative Analysis of VR Simulations for Chemistry Education

Applied Sciences
It is hard to envision a modern world where information technology does not facilitate daily tasks, including learning and teaching. This paper explores the use of virtual reality (VR) simulations in chemistry education, focusing on how immersive VR ...
Jamshid Kayumov, Durbek Usmanov, Ugiloy Yusupova, Zulayho Smanova, Bakhtiyor Rasulev   +4 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Creating a Sustainable Future: Some Philosophical and Educational Considerations for Chemistry Teaching [PDF]

, 2013
The International Union of Pure and Applied Chemistry (IUPAC) and UNESCO have proposed that the International Year of Chemistry, 2011, should make a strong educational contribution to the goals of the UN Decade of Education for Sustainable Development ...
Gil Pérez, Daniel, Vilches Peña, Amparo   +1 more
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Making Redox Tangible: Physical Models in Electrochemistry Education

Education Sciences
This study addresses the persistent challenges that students face in understanding redox reactions, particularly the link between symbolic and particulate representations in electrochemistry. The purpose was to explore whether physical modeling with clay
Karina Adbo, Gunilla Akesson-Nilsson
doaj   +1 more source

Teaching of Undergraduate Chemistry Education Courses Through Information and Communication Technology Integration [PDF]

, 2019
Florence Obiageli Ezeudu, Florence O. Attah, Stephen Chinedu Nwafor   +2 more
openalex   +1 more source