Results 71 to 80 of about 1,016,132 (353)

A Problem with STEM [PDF]

open access: yes, 2013
Striking differences between physics and biology have important implications for interdisciplinary science, technology, engineering, and mathematics (STEM) education. I am a physicist with interdisciplinary connections. The research group in which I work,
Marder, Michael
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Chemistry course for radiochemistry engineers on the platform Moodle: a support to self-education for undergraduate students [PDF]

open access: yes, 2011
The education challenges at present times include the incorporation of information and communication technologies (ICT) in the learning-teaching process.
Jáuregui Haza, Ulises Javier   +2 more
core  

Spotlight on Medicinal Chemistry Education [PDF]

open access: yesFuture Medicinal Chemistry, 2014
The field of medicinal chemistry is constantly evolving and it is important for medicinal chemists to develop the skills and knowledge required to succeed and contribute to the advancement of the field. Future Medicinal Chemistry spoke with Simone Pitman (SP), Yao-Zhong Xu (YX), Peter Taylor (PT) and Nick Turner (NT) from The Open University (OU ...
Pitman, Simone   +3 more
openaire   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

A New ‘Idea of Nature’ for Chemical Education [PDF]

open access: yes, 2013
This paper recommends that chemistry educators shift to a different ‘idea of nature’, an alternative ‘worldview.’ Much of contemporary science and technology deals in one way or another with dynamic coherences that display novel and important properties.
Earley, Joseph E.
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Chemistry Education in Bosnia and Herzegovina

open access: yesCenter for Educational Policy Studies Journal, 2020
In this paper, the education system in Bosnia and Herzegovina is presented in the light of current state-level legislation, with an emphasis on chemistry education at the primary, secondary and tertiary level.
Meliha Zejnilagić-Hajrić , Ines Nuić
doaj   +1 more source

The effects of the design and development of a chemistry curriculum reform on teachers’ professional growth: a case study [PDF]

open access: yes, 2010
A curriculum innovation requires new learning material for students and a preparation program for teachers, in which teacher learning is a key ingredient.
Coenders, Fer   +3 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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