Results 111 to 120 of about 721,337 (349)

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Activities of the Unit for Forensic Chemistry and Toxicology of the Swiss Society of Legal Medicine

open access: yesCHIMIA, 1997
In Switzerland, analytical toxicology and chemistry in the Forensic Medicine are scientifically organized around the Swiss Society of Legal Medicine.
Laurent Rivier
doaj  

Food Physical Chemistry and Biophysical Chemistry

open access: yes, 2011
Food Physical Chemistry is considered to be a branch of Food Chemistry^1,2^ concerned with the study of both physical and chemical interactions in foods in terms of physical and chemical principles applied to food systems, as well as the applications of ...
I. C. Baianu, I.C. Baianu
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Analytical Chemistry: Techniques and Methods

open access: yes
"Analytical Chemistry Techniques and Methods" is designed for both undergraduate and postgraduate students in analytical chemistry, providing thorough discussions on key concepts and techniques. The book explores classical methods, including complexometric and redox titrations, along with a variety of spectroscopic and separation techniques, thermal ...
openaire   +2 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Analytical Chemistry 3 (Instrumental Techniques)

open access: yes, 2014
Exam paper for second semester National Diploma (Analytical Chemistry (3 years) ; Analytical Chemistry (4 ...
University of Johannesburg
core  

Analytical Chemistry Nutritional Insights: Exploring ED-XRF, LIBS, and Chemometric Techniques for Macronutrient Determination in Non-conventional Food Plants (PANC)

open access: yes
Non-conventional food plants (PANC) warrant considerable attention in scientific research. The modern emphasis on cultivating a wholesome diet devoid of additives, preservatives, and artificial colors while being functional and requiring minimal ...
Pereira-Filho, Edenir Rodrigues   +2 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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