Results 91 to 100 of about 656,473 (300)
Recent trends in microsampling and reduced-volume sample preparation procedures
Advances in Sample PreparationThe emergence of Green Chemistry (GC), Green Analytical Chemistry (GAC), and Green Sample Preparation (GSP) has significantly influenced the evolution of sample preparation techniques.
Miryam Perrucci +6 more
doaj +1 more source
Spatial Analyses of Specialized Metabolites: The Key to Studying Function in Hosts
mSystems, 2018 Microbial communities contribute to a wide variety of biological functions in hosts and have the ability to specifically influence the health of those organisms through production of specialized metabolites.
Melissa M. Galey, Laura M. Sanchez
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Greenness metrics for analytical methodologies linked to mass spectrometry
Green Analytical ChemistryWith a global focus on sustainability and environmental impact, scientists have been prompted to adopt eco-friendly practices. Green analytical chemistry (GAC) promotes energy-efficient equipment, reduction of toxic chemicals, and sustainable waste ...
Marina Jurisch +7 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Activities of the Unit for Forensic Chemistry and Toxicology of the Swiss Society of Legal Medicine
CHIMIA, 1997 In Switzerland, analytical toxicology and chemistry in the Forensic Medicine are scientifically organized around the Swiss Society of Legal Medicine.
Laurent Rivier
doaj
Characterization of gold nanoparticle layer deposited on gold electrode by various techniques for improved sensing abilities [PDF]
, 2016 The deposition of gold nanoparticles (AuNPs) on the surface of gold electrode is believed to enhance the electrochemical characteristics of the surface. According to the existing literature, this could be performed in various ways.
Adriaens, Mieke +8 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source