Results 81 to 90 of about 656,473 (300)

Compositional Analysis of the High Molecular Weight Ethylene Oxide Propylene Oxide Copolymer by MALDI Mass Spectrometry

, 2012
The composition of narrow distribution poly ethylene oxide-propylene oxide copolymer (Mw ~ 8700 Da) was studied using matrix assisted laser desorption ionization (MALDI) mass spectrometry.
Houshia, Orwa Jaber, Wilkins, Charles
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Distributed environmental monitoring [PDF]

, 2013
With increasingly ubiquitous use of web-based technologies in society today, autonomous sensor networks represent the future in large-scale information acquisition for applications ranging from environmental monitoring to in vivo sensing.
Cleary, John, Collins, Fiachra, Diamond, Dermot, Fay, Cormac, Zuliani, Claudio   +4 more
core  

Exploring the physical limits of saturation contrast in Magnetic Resonance Imagign [PDF]

, 2012
Magnetic Resonance Imaging has become nowadays an indispensable tool with applications ranging from medicine to material science. However, so far the physical limits of the maximum achievable experimental contrast were unknown.
Glaser, S. J., Janich, M., Lapert, M., Sugny, D., Zhang, Y.   +4 more
core   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Current advances in solid-phase microextraction technique as a green analytical sample preparation approach

Green Chemistry Letters and Reviews
Conventional analytical techniques often rely on harmful chemicals, leading to significant environmental pollution, contamination, and waste generation.
Harshika Poojary, Keerthana Selvamuthukumar, Roshna Parveen, Gouri Illanad, Debsmita Mandal, Sophia Koo, Chiranjit Ghosh   +6 more
doaj   +1 more source

The Impact of a National Science Foundation Collaborative for Excellence in Teacher Preparation on an Undergraduate Chemistry Course for Non-Chemistry Science Majors [PDF]

, 2000
In 1999 and 2000 Chemistry 312: Analytical Chemistry for non-chemistry science majors (taken in the junior or senior year), was revised as a result of the instructor’s involvements in the Center for Excellence in Teacher Preparation project and an NSF ...
Tyson, J.
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Recent progress in field-directed assembly of colloids in an evaporating droplet

Materials Today Bio
Evaporation-driven self-assembly of colloidal particles in a sessile drop can construct simple structures in various scenarios. However, the non-equilibrium self-assembly process, dominated by internal capillary flow and solute- or thermal-induced ...
Yongqing He, Jian Liu, Xukai Yang, Jianzhi Yang, Feng Jiao   +4 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source